The pathophysiology of atopic dermatitis is complex and multifactorial, involving elements of
barrier dysfunction, alterations in cell mediated immune responses, IgE mediated …

Contact dermatitis is produced by external skin exposure to an allergen, but sometimes a
systemically administered allergen may reach the skin and remain concentrated there with …

Some cutaneous inflammations are induced by percutaneous exposure to foreign Ags, and
many chemical mediators regulate this inflammation process. One of these mediators …

Nickel (Ni), the main cause of contact allergy to metals, induces in vitro production of both
Th1-and Th2-type cytokines in peripheral blood mononuclear cells (PBMC) from allergic …

Background Nickel‐induced proliferation or cytokine release by peripheral blood
mononuclear cells may be used for in vitro diagnosis of nickel allergy. Objectives Aim of this …

Over the 20th century, the frequent use of nickel in consumer products resulted in an
increasing prevalence of nickel allergy. Risk items included suspenders in the 1950s …

Abstract Purpose of Review Atopic dermatitis (AD) remains a dermatological disease that
imposes a significant burden on society. Air pollution has previously been linked to both the …

Background Diagnostic patch testing in allergic contact dermatitis faces the risk of boosting
existing hypersensitivities or active sensitization. Risk‐free and reliable in vitro assays using …

To date, no in vitro test is suitable for routine diagnosis of contact allergy. The aim of our
study was to establish improved in vitro test protocol for the detection of antigen‐specific …

Objective: To determine the prevalence of nickel allergy in a sample of orthodontic patients
and longitudinally compare the clinical periodontal status of these individuals with that of a …