Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction

Z Zheng, Y Tan, Y Li, Y Liu, G Yi, CY Yu… - Journal of Controlled …, 2021 - Elsevier
Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

Invasome: A novel nanocarrier for transdermal drug delivery

S Babaie, AR Del Bakhshayesh, JW Ha… - Nanomaterials, 2020 - mdpi.com
Invasomes are novel vesicular systems that exhibit improved transdermal penetration
compared to conventional liposomes. These vesicles contain phospholipids, ethanol, and …

Essential oils and isolated terpenes in nanosystems designed for topical administration: A review

SP de Matos, HF Teixeira, ÁAN De Lima… - Biomolecules, 2019 - mdpi.com
Essential oils are natural products with a complex composition. Terpenes are the most
common class of chemical compounds present in essential oils. Terpenes and the essential …

Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application

B Maddiboyina, H Roy, RK Nakkala… - Chemical Biology & …, 2023 - Wiley Online Library
Multidrug resistance in breast cancer and the associated side‐effects of anticancer therapies
are significant hurdles in chemotherapy‐based treatment. Biodegradable polymeric nano …

Pharmacokinetic evaluation of the synergistic effect of raloxifene loaded transfersomes for transdermal delivery

S Mahmood, B Chatterjee, UK Mandal - Journal of Drug Delivery Science …, 2021 - Elsevier
The current research work involves the comparative evaluation of the synergistic potential of
transfersomes with span 80, span 85 for transdermal delivery of raloxifene hydrochloride …

Mechanistic advances in osteoporosis and anti‐osteoporosis therapies

H Wang, Y Luo, H Wang, F Li, F Yu, L Ye - MedComm, 2023 - Wiley Online Library
Osteoporosis is a type of bone loss disease characterized by a reduction in bone mass and
microarchitectural deterioration of bone tissue. With the intensification of global aging, this …

Recent advances in cyclization reactions of isatins or thioisatins via C–N or C–S bond cleavage

J Shen, L Zhang, X Meng - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The exploration of new reactivity modes and synthetic methods has always been an
attractive goal of organic and medicinal chemistry. As potential raw materials for the efficient …

Drug delivery system based on minoxidil nanoparticles promotes hair growth in C57BL/6 mice

N Nagai, Y Iwai, A Sakamoto, H Otake… - International Journal …, 2019 - Taylor & Francis
Purpose We designed formulations based on minoxidil (MXD) nanoparticles (N-MXD) and
examined whether N-MXD can increase drug delivery into the follicles. In addition, we …

Formulation development for transdermal delivery of raloxifene, a chemoprophylactic agent against breast cancer

D Vora, A Dandekar, S Bhattaccharjee, ON Singh… - Pharmaceutics, 2022 - mdpi.com
Raloxifene (RLX) is a second-generation selective estrogen receptor modulator approved
for the prevention of invasive breast cancer in women. Oral therapy of RLX requires daily …

Water/pH dual responsive in situ calcium supplement collaborates simvastatin for osteoblast promotion mediated osteoporosis therapy via oral medication

S Tao, F Yu, Y Song, W Zhou, J Lv, R Zhao… - Journal of Controlled …, 2021 - Elsevier
Calcium supplement is the most commonly adopted treatment for osteoporosis but usually
requires high dose and frequency. The modality of calcium supplement is therefore …