RNA adopts 3D structures that confer varied functional roles in human biology and
dysfunction in disease. Approaches to therapeutically target RNA structures with small …

Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …

Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …

Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Ferroptosis, spurred by excess labile iron and lipid peroxidation, is implicated in various
diseases. Advances have been made in comprehending the lipid-peroxidation side of …

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

Iron is critical for the appearance and maintenance of life on Earth. Almost all organisms
compete or cooperate for iron acquisition, demonstrating the importance of this essential …

Trace elements, such as iodine and selenium (Se), are vital to human health and play an
essential role in metabolism. They are also important to thyroid metabolism and function …

Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and …

Ferroptosis is a novel form of programmed cell death in which the accumulation of
intracellular iron promotes lipid peroxidation, leading to cell death. Recently, the induction of …