Role of hormones, genes, and environment in human cryptorchidism

C Foresta, D Zuccarello, A Garolla, A Ferlin - Endocrine reviews, 2008 - academic.oup.com
Cryptorchidism is the most frequent congenital birth defect in male children (2–4% in full-
term male births), and it has the potential to impact the health of the human male. In fact …

Gr/gr deletions on Y-chromosome correlate with male infertility: an original study, Meta-Analyses and trial sequential analyses

SK Bansal, D Jaiswal, N Gupta, K Singh, R Dada… - Scientific reports, 2016 - nature.com
We analyzed the AZFc region of the Y-chromosome for complete (b2/b4) and distinct partial
deletions (gr/gr, b1/b3, b2/b3) in 822 infertile and 225 proven fertile men. We observed …

Partial AZFc deletions and duplications: clinical correlates in the Italian population

C Giachini, I Laface, E Guarducci, G Balercia, G Forti… - Human genetics, 2008 - Springer
The role of partial AZFc deletions of the Y chromosome in spermatogenic impairment is
currently debated. Recently, it was also reported that duplications of the same region are …

The Y chromosome and male infertility

H Sadeghi-Nejad, RD Oates - Current Opinion in Urology, 2008 - journals.lww.com
The Y chromosome and male infertility : Current Opinion in Urology The Y chromosome and
male infertility : Current Opinion in Urology Log in or Register Subscribe to journalSubscribe …

Phenotypic variation within European carriers of the Y-chromosomal gr/gr deletion is independent of Y-chromosomal background

C Krausz, C Giachini, Y Xue, MK O'Bryan… - Journal of medical …, 2009 - jmg.bmj.com
Background: Previous studies have compared sperm phenotypes between men with partial
deletions within the AZF c region of the Y chromosome and non-carriers, with variable …

Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number

C Mau Kai, A Juul, K McElreavey… - Human …, 2008 - academic.oup.com
BACKGROUND Deletions in the azoospermia factor (AZF) region of the Y chromosome are
frequent in infertile men. The clinical consequences and the mode of inheritance of these …

Do we need to search for gr/gr deletions in infertile men in a clinical setting?

K Stouffs, H Tournaye, J Van der Elst… - Human …, 2008 - academic.oup.com
BACKGROUND Partial deletions of the AZFc region of the Y chromosome such as gr/gr
deletions have been detected in infertile patients as well as in control groups. The impact of …

Detection of partial AZFc microdeletions in azoospermic infertile men is not informative of microTESE outcome

A Miraghazadeh, MAS Gilani… - … Journal of Fertility & …, 2018 - pmc.ncbi.nlm.nih.gov
Background Microdeletions of the Yq chromosome are among the most frequent genetic
etiological factor of male infertility which spans the azoospermia factor regions (AZFa, AZFb …

Further insights into the role of T222P variant of RXFP2 in non‐syndromic cryptorchidism in two Mediterranean populations

E Ars, D Lo Giacco, L Bassas, F Nuti… - … journal of andrology, 2011 - Wiley Online Library
The aetiopathogenesis of isolated cryptorchidism remains largely unknown. Mutation
screenings in the most relevant candidate genes for testicular maldescent lead to …

Analysis of DAZL SNP260 and SNP386 in infertile Chinese males using multi-analyte suspension array

Y Zhu, M Ma, L Wan, D Zhang… - Molecular …, 2014 - spandidos-publications.com
The aim of the present study was to investigate the association between two single
nucleotide polymorphisms (SNPs) and infertility in Chinese males using multi-analyte …