Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

JG Croissant, KS Butler, JI Zink, CJ Brinker - Nature Reviews Materials, 2020 - nature.com
Natural silica and silicates are predominantly crystalline and constitute the most abundant
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …

[HTML][HTML] Toxicology of silica nanoparticles: an update

S Murugadoss, D Lison, L Godderis… - Archives of …, 2017 - Springer
Large-scale production and use of amorphous silica nanoparticles (SiNPs) have increased
the risk of human exposure to SiNPs, while their health effects remain unclear. In this review …

The toxicity of silica nanoparticles to the immune system

L Chen, J Liu, Y Zhang, G Zhang, Y Kang, A Chen… - …, 2018 - Taylor & Francis
Silicon-based materials and their oxides are widely used in drug delivery, dietary
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …

Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles

C Pavan, R Santalucia, R Leinardi, M Fabbiani… - Proceedings of the …, 2020 - pnas.org
Inhalation of silica particles can induce inflammatory lung reactions that lead to silicosis
and/or lung cancer when the particles are biopersistent. This toxic activity of silica dusts is …

The size-dependent cytotoxicity of amorphous silica nanoparticles: a systematic review of in vitro studies

X Dong, Z Wu, X Li, L **ao, M Yang, Y Li… - International Journal …, 2020 - Taylor & Francis
With the increasing production and application of engineered amorphous silica
nanoparticles (aSiNPs), people have more opportunities to be exposed to aSiNPs. However …

[HTML][HTML] Magnetic iron nanoparticles: synthesis, surface enhancements, and biological challenges

JR Vargas-Ortiz, C Gonzalez, K Esquivel - Processes, 2022 - mdpi.com
This review focuses on the role of magnetic nanoparticles (MNPs), their physicochemical
properties, their potential applications, and their association with the consequent …

The impact of coal mine dust characteristics on pathways to respiratory harm: Investigating the pneumoconiotic potency of coals

C Kamanzi, M Becker, M Jacobs, P Konečný… - Environmental …, 2023 - Springer
Exposure to dust from the mining environment has historically resulted in epidemic levels of
mortality and morbidity from pneumoconiotic diseases such as silicosis, coal workers' …

Carrageenan-based nano-hybrid materials for the mitigation of hazardous environmental pollutants

W Li, SA Qamar, M Qamar, A Basharat, M Bilal… - International Journal of …, 2021 - Elsevier
Fast industrialization and population growth are associated with the increased release of
hazardous contaminants in the environment. These hazardous substances, including …

[HTML][HTML] Pulmonary toxicity of silica linked to its micro-or nanometric particle size and crystal structure: A review

V Marques Da Silva, M Benjdir, P Montagne, JC Pairon… - Nanomaterials, 2022 - mdpi.com
Silicon dioxide (SiO2) is a mineral compound present in the Earth's crust in two mineral
forms: crystalline and amorphous. Based on epidemiological and/or biological evidence, the …

The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

C Pavan, M Delle Piane, M Gullo, F Filippi… - Particle and fibre …, 2019 - Springer
Background Silica continues to represent an intriguing topic of fundamental and applied
research across various scientific fields, from geology to physics, chemistry, cell biology, and …