Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and
contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Myocardial infarction irreversibly destroys millions of cardiomyocytes in the ventricle, making
it the leading cause of heart failure worldwide. Over the past two decades, many progenitor …

Obesity and increased lipid availability have been implicated in the development and
progression of chronic kidney disease. One of the major sites of renal lipid accumulation is …

Background: Nuclear factor-erythroid related factor-2 (Nrf2) is a master regulator of
transcriptional activation of anti-oxidants in cells. Similarly, heme oxygenase (HO) is a …