The copper metabolism disorder Wilson's disease was first defined in 1912. Wilson's
disease can present with hepatic and neurological deficits, including dystonia and …

Progressive hepatolenticular degeneration, or Wilson's disease, is a genetic disorder of
copper metabolism. Knowledge of the clinical presentations and treatment of the disease …

Copper is an essential metal required for many metalloproteins' function. A fraction of dietary
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

Background: Clinical presentations of Wilson's disease (WD) in childhood ranges from
asymptomatic liver disease to cirrhosis or acute liver failure, whereas neurological and …

Copper is an essential metal that is an important cofactor for many proteins. The average
diet provides substantial amounts of copper, typically 2-5 mg/day; the recommended intake …

Clinical practice guidelines for Wilson's disease (WD) have been published by the American
Association for the Study of Liver Diseases and European Association for the Study of the …

Objective To review the current evidence about psychiatric symptoms in Wilson's disease
(WD). Method We searched Ovid, PsychInfo, CINHAL and PubMed databases from May …

Wilson's disease (WD) is an inherited metabolic disorder related to disturbances of copper
metabolism, and predominantly presents with liver and neuropsychiatric symptoms. In most …

Wilson's disease (WD), which results from the defective ATP7B protein product, is
characterized by impaired copper metabolism and its clinical consequences vary from an …