Proteogenomic data and resources for pan-cancer analysis

Y Li, Y Dou, FDV Leprevost, Y Geffen, AP Calinawan… - Cancer cell, 2023 - cell.com
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …

The rsna-asnr-miccai brats 2021 benchmark on brain tumor segmentation and radiogenomic classification

U Baid, S Ghodasara, S Mohan, M Bilello… - arxiv preprint arxiv …, 2021 - arxiv.org
The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the
Radiological Society of North America (RSNA), the American Society of Neuroradiology …

Transcriptome analysis reveals tumor microenvironment changes in glioblastoma

Y Hoogstrate, K Draaisma, SA Ghisai, L van Hijfte… - Cancer Cell, 2023 - cell.com
A better understanding of transcriptional evolution of IDH-wild-type glioblastoma may be
crucial for treatment optimization. Here, we perform RNA sequencing (RNA-seq)(n= 322 test …

[HTML][HTML] Proteogenomic characterization of pancreatic ductal adenocarcinoma

L Cao, C Huang, DC Zhou, Y Hu, TM Lih, SR Savage… - Cell, 2021 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways

Y Zhang, F Chen, DS Chandrashekar… - Nature …, 2022 - nature.com
Mass-spectrometry-based proteomic data on human tumors—combined with corresponding
multi-omics data—present opportunities for systematic and pan-cancer proteogenomic …

[HTML][HTML] A proteogenomic portrait of lung squamous cell carcinoma

S Satpathy, K Krug, PMJ Beltran, SR Savage, F Petralia… - Cell, 2021 - cell.com
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

Cancer proteogenomics: current impact and future prospects

DR Mani, K Krug, B Zhang, S Satpathy… - Nature Reviews …, 2022 - nature.com
Genomic analyses in cancer have been enormously impactful, leading to the identification of
driver mutations and development of targeted therapies. But the functions of the vast majority …