[HTML][HTML] Advances in electroactive biomaterials: through the lens of electrical stimulation promoting bone regeneration strategy

S Luo, C Zhang, W **ong, Y Song, Q Wang… - Journal of Orthopaedic …, 2024‏ - Elsevier
The regenerative capacity of bone is indispensable for growth, given that accidental injury is
almost inevitable. Bone regenerative capacity is relevant for the aging population globally …

Bioelectric signaling: role of bioelectricity in directional cell migration in wound healing

M Zhao, M Rolandi, RR Isseroff - Cold Spring Harbor …, 2022‏ - cshperspectives.cshlp.org
In wound healing, individual cells' behaviors coordinate movement toward the wound center
to restore small or large barrier defects. The migration of epithelial cells as a continuous …

Bioelectronic microfluidic wound healing: a platform for investigating direct current stimulation of injured cell collectives

S Shaner, A Savelyeva, A Kvartuh, N Jedrusik… - Lab on a Chip, 2023‏ - pubs.rsc.org
Upon cutaneous injury, the human body naturally forms an electric field (EF) that acts as a
guidance cue for relevant cellular and tissue repair and reorganization. However, the direct …

Electrotaxis evokes directional separation of co-cultured keratinocytes and fibroblasts

J Leal, S Shaner, N Jedrusik, A Savelyeva… - Scientific Reports, 2023‏ - nature.com
Bioelectric communication plays a significant role in several cellular processes and
biological mechanisms, such as division, differentiation, migration, cancer metastasis, and …

Bioelectric stimulation controls tissue shape and size

G Shim, IB Breinyn, A Martínez-Calvo, S Rao… - Nature …, 2024‏ - nature.com
Epithelial tissues sheath organs and electro-mechanically regulate ion and water transport
to regulate development, homeostasis, and hydrostatic organ pressure. Here, we …

Collective buoyancy-driven dynamics in swarming enzymatic nanomotors

S Chen, X Peetroons, AC Bakenecker… - Nature …, 2024‏ - nature.com
Enzymatic nanomotors harvest kinetic energy through the catalysis of chemical fuels. When
a drop containing nanomotors is placed in a fuel-rich environment, they assemble into …

Purse-string contraction guides mechanical gradient-dictated heterogeneous migration of epithelial monolayer

H Zhang, H Xu, W Sun, X Fang, P Qin, J Huang, J Fang… - Acta Biomaterialia, 2023‏ - Elsevier
Mechanical heterogeneity has been recognized as an important role in mediating collective
cell migration, yet the related mechanism has not been elucidated. Herein, we fabricate …

Near-Infrared Stimuli-Responsive Hydrogel Promotes Cell Migration for Accelerated Diabetic Wound Healing

W Zhao, L Qiang, C Zhang, S Li, Y Liu… - … Applied Materials & …, 2024‏ - ACS Publications
Diabetic wound healing including diabetic foot ulcers is a major clinical challenge, which
could bring an increased level of mortality and morbidity. However, conventional wound …

An emerging frontier in intercellular communication: extracellular vesicles in regeneration

PN Avalos, DJ Forsthoefel - Frontiers in Cell and Developmental …, 2022‏ - frontiersin.org
Regeneration requires cellular proliferation, differentiation, and other processes that are
regulated by secreted cues originating from cells in the local environment. Recent studies …

Short-term bioelectric stimulation of collective cell migration in tissues reprograms long-term supracellular dynamics

AE Wolf, MA Heinrich, IB Breinyn, TJ Zajdel… - PNAS …, 2022‏ - academic.oup.com
The ability to program collective cell migration can allow us to control critical multicellular
processes in development, regenerative medicine, and invasive disease. However, while …