TMEM16A as a potential treatment target for head and neck cancer

K Okuyama, S Yanamoto - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Abstract Transmembrane protein 16A (TMEM16A) forms a plasma membrane-localized
Ca2+-activated Cl-channel. Its gene has been mapped to an area on chromosome 11q13 …

[HTML][HTML] The potential role of HPV oncoproteins in the PD-L1/PD-1 pathway in cervical cancer: new perspectives on cervical cancer immunotherapy

J Li, Y Ma, Q Wu, P **, J Li, X Xu - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Cervical cancer (CC) is a common malignant tumour of the female reproductive system that
is highly harmful to women's health. The efficacy of traditional surgery, radiotherapy and …

[HTML][HTML] The cGAS/STING/IFN-1 response in squamous head and neck cancer cells after genotoxic challenges and abrogation of the ATR-Chk1 and Fanconi anemia …

S Zahnreich, S El Guerzyfy, J Kaufmann… - International journal of …, 2023 - mdpi.com
Locally advanced head and neck squamous cell carcinomas (HNSCC) are often refractory
to platinum-based radiochemotherapy and new immuno-oncological strategies. To stimulate …

Integrative analysis of m7G methylation-associated genes prognostic signature with immunotherapy and identification of LARP1 as a key oncogene in head and neck …

J Xu, Z You, Z Zhu, M Liu, Z Zhang, P Xu… - Frontiers in …, 2025 - frontiersin.org
Background N7-methylguanosine (m7G) methylation is an RNA modification associated with
cancer progression, but its specific role in head and neck squamous cell carcinoma …

Hypoxia and acidity regulate immune checkpoint molecule and IFN-β expression in non-small cell lung cancer cell lines

AG Mitrakas, A Giatromanolaki… - Journal of Receptors …, 2023 - Taylor & Francis
Purpose Non-small cell lung cancer (NSCLC) is one of the most lethal tumors in humans.
Immunotherapy with immune checkpoint inhibitors (ICIs) has revolutionized the treatment of …

An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic …

IL Co, C Yu, S Lamorte, MT Ciudad, N Landon-Brace… - bioRxiv, 2023 - biorxiv.org
In pancreatic ductal adenocarcinoma (PDAC), tumour associated macrophages (TAMs) are
a heterogeneous immune cell population that interact with cancer cells to promote …

Factors predicting early death in head and neck cancer

C Talani - 2024 - diva-portal.org
Head and neck cancer (HNC) ranks as the seventh most common cancer worldwide. Nearly
890,000 cases and 450,000 deaths were reported in 2020. The majority (90%) of HNC …