A unique organelle for studying membrane biochemistry is the mitochondrion whose
functionality depends on a coordinated supply of proteins and lipids. Mitochondria are …

Non-alcoholic fatty liver disease encompasses a spectrum of liver diseases, including
simple steatosis, steatohepatitis, liver fibrosis and cirrhosis and hepatocellular carcinoma …

As a branch of metabolomics, lipidomics is aimed at full analysis of lipid species and their
biological roles with respect to health and diseases and has attracted increasing attention of …

Brain mitochondria are fundamental to maintaining healthy functional brains, and their
dysfunction is involved in age-related neurodegenerative disorders such as Alzheimer's …

The function of biological cells is intimately associated with their internal organization, in
which multiple subcellular structures have specialized roles. Such subcellular structures …

Mitochondria are arbiters in the fragile balance between cell life and death. These
organelles present an intricate membrane system, with a peculiar lipid composition and …

Brain lipid homeostasis plays an important role in Alzheimer's disease (AD) and other
neurodegenerative disorders. Aggregation of amyloid-β peptide is one of the major events in …

Combination of AChE inhibiting and histamine H3 receptor antagonizing properties in a
single molecule might show synergistic effects to improve cognitive deficits in Alzheimer's …

This work illustrates reactive desorption electrospray ionization mass spectrometry (DESI-
MS) with a stable dication on biological tissues. Rat brain and zebra fish tissues were …

The present study aimed for the development and in-vitro/in-vivo evaluation of tacrine
loaded poly-(D, l)-lactide-co-glycolide nanoparticles (TCR-PLGA NPs) for the treatment of …