Breast cancer is a common malignancy among women worldwide. Regardless of the
economic status of a country, breast cancer poses a burden in prevention, diagnosis and …

Functional specialization of cells and tissues in metazoans require specific gene expression
patterns. Biological processes, thus, need precise temporal and spatial coordination of gene …

Background Intensive evidence has highlighted the effect of aberrant alternative splicing
(AS) events on cancer progression when triggered by dysregulation of the SR protein family …

Breast cancer has become the most common type of cancers worldwide. Its high prevalence
and malignant features are associated with various environmental factors and molecules …

Summary The bromodomain protein 4 (BRD4) is an atypical kinase and histone acetyl
transferase (HAT) that binds to acetylated histones and contributes to chromatin remodeling …

The dysregulation of the splicing process has emerged as a novel hallmark of metabolic and
tumor pathologies. In breast cancer (BCa), which represents the most diagnosed cancer …

Human epidermal growth factor receptor 2 (ERBB2 or HER2) amplification/overexpression
is associated with a particularly aggressive molecular subtype of breast cancer (BC) …

Breast cancer is known to be a heterogeneous disease driven by a large repertoire of
molecular abnormalities, which contribute to its diverse clinical behaviour. Despite the …

Dysregulation of Transglutaminase type 2 through GATA3 defines aggressiveness and
Doxorubicin sensitivity in breast cancer - PMC Back to Top Skip to main content NIH NLM Logo …

Breast cancer, a multi‐networking heterogeneous disease, has emerged as a serious
impediment to progress in clinical oncology. Although technological advancements and …