Mental health researchers and clinicians have long sought answers to the question “What
works for whom?” The goal of precision medicine is to provide evidence-based answers to …

Objectives Improving Access to Psychological Therapies (IAPT) is a national‐level
dissemination programme for provision of evidence‐based psychological treatments for …

This chapter sets out the current status of the evidence-base for the efficacy and
effectiveness of psychological therapies. First, methods for eliciting and synthesizing …

Importance Depression is a major cause of disability worldwide. Although empirically
supported treatments are available, there is scarce evidence on how to effectively …

This chapter addresses fundamental issues of change in psychotherapy: how to measure,
monitor, predict change, and provide feedback on treatment outcome. The chapter starts …

Background Previous research suggests that the use of outcome feedback technology can
enable psychological therapists to identify and resolve obstacles to clinical improvement …

The goal of this chapter is to survey practice-based evidence (PBE) in the psychological
therapies that has accumulated over the last decade. PBE, or practice-oriented research …

Objective: There is a need for rigorous methods to study the mechanisms that lead to
individual-level change (ie, process-outcome research). We argue that panel data (ie …

There are large health, societal, and economic costs associated with attrition from
psychological services. The recently emerged, innovative statistical tool of complex network …

Risk and prognosis are central concepts in precision medicine, referring to the probability of
future outcomes in people with a particular health condition. Prognosis research has a long …