Eosinophilic esophagitis: a review

A Muir, GW Falk - Jama, 2021 - jamanetwork.com
Importance Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory
disease of the esophagus that affects an estimated 34.4/100 000 people in Europe and …

Thymic stromal lymphopoietin isoforms, inflammatory disorders, and cancer

G Varricchi, A Pecoraro, G Marone… - Frontiers in …, 2018 - frontiersin.org
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …

ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)

ES Dellon, N Gonsalves, I Hirano… - Official journal of the …, 2013 - journals.lww.com
Esophageal eosinophilia and eosinophilic esophagitis (EoE) are increasingly recognized
and prevalent conditions, which now represent common clinical problems encountered by …

Eosinophilic esophagitis: updated consensus recommendations for children and adults

CA Liacouras, GT Furuta, I Hirano, D Atkins… - Journal of Allergy and …, 2011 - Elsevier
Eosinophilic esophagitis (EoE) is a clinicopathologic condition of increasing recognition and
prevalence. In 2007, a consensus recommendation provided clinical and histopathologic …

The atopic march: current insights into skin barrier dysfunction and epithelial cell‐derived cytokines

H Han, F Roan, SF Ziegler - Immunological reviews, 2017 - Wiley Online Library
Atopic dermatitis often precedes the development of other atopic diseases. The atopic march
describes this temporal relationship in the natural history of atopic diseases. Although the …

Eosinophil knockout humans: uncovering the role of eosinophils through eosinophil-directed biological therapies

EA Jacobsen, DJ Jackson, E Heffler… - Annual review of …, 2021 - annualreviews.org
The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

PA Lyons, JE Peters, F Alberici, J Liley… - Nature …, 2019 - nature.com
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of
unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) …

Wheat allergy: diagnosis and management

A Cianferoni - Journal of asthma and allergy, 2016 - Taylor & Francis
Triticum aestivum (bread wheat) is the most widely grown crop worldwide. In genetically
predisposed individuals, wheat can cause specific immune responses. A food allergy to …

Targeting eosinophils in allergy, inflammation and beyond

PC Fulkerson, ME Rothenberg - Nature reviews Drug discovery, 2013 - nature.com
Eosinophils can regulate local immune and inflammatory responses, and their accumulation
in the blood and tissue is associated with several inflammatory and infectious diseases …

The genetics of asthma and allergic disease: a 21st century perspective

C Ober, TC Yao - Immunological reviews, 2011 - Wiley Online Library
Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …