Congenital colobomata of the eye are important causes of childhood visual impairment and
blindness. Ocular coloboma can be seen in isolation and in an impressive number of …

Mowat-Wilson syndrome (MWS) is a multiple congenital anomaly syndrome characterized
by a distinct facial phenotype (high forehead, frontal bossing, large eyebrows, medially …

Optic fissure closure requires precise orchestration in timing and apposition of two poles of
the optic cup. The relative roles of genetics and environment on this process remain elusive …

Mowat‐Wilson syndrome (MWS) is a recently delineated mental retardation (MR)‐multiple
congenital anomaly syndrome, characterized by typical facies, severe MR, epilepsy, and …

Myopia can cause severe visual impairment. Here, we report a two-stage genome-wide
association study for three myopia-related traits in 9,804 Japanese individuals, which was …

Embryonic development of the vertebrate eye begins with the formation of an optic vesicle
which folds inwards to form a double-layered optic cup with a fissure on the ventral surface …

Mowat–Wilson Syndrome is a recently delineated mental retardation syndrome usually
associated with multiple malformations and a recognizable facial phenotype caused by …

In 1998, Mowat et al. described six patients with a new syndrome characterized by mental
retardation, a distinct facial appearance, microcephaly and Hirschsprung disease (HSCR) …

Hirschsprung's disease (HSCR) is a complex congenital disorder which, from a molecular
perspective, appears to result due to disruption of normal signalling during development of …

Severe myopia (defined as spherical equivalent<− 6.0 D) is a predominant problem in Asian
countries, resulting in substantial morbidity. We performed a meta-analysis of four genome …