Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications

PT van Leeuwen, S Brul, J Zhang… - FEMS microbiology …, 2023 - academic.oup.com
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …

Targeting nonalcoholic fatty liver disease via gut microbiome-centered therapies

M Koning, H Herrema, M Nieuwdorp… - Gut Microbes, 2023 - Taylor & Francis
Humans possess abundant amounts of microorganisms, including bacteria, fungi, viruses,
and archaea, in their gut. Patients with nonalcoholic fatty liver disease (NAFLD) exhibit …

The Weissella genus: Clinically treatable bacteria with antimicrobial/probiotic effects on inflammation and cancer

S Ahmed, S Singh, V Singh, KD Roberts, A Zaidi… - Microorganisms, 2022 - mdpi.com
Weissella is a genus earlier considered a member of the family Leuconostocaceae, which
was reclassified into the family Lactobacillaceae in 1993. Recently, there have been studies …

Bioactive compounds for human and planetary health

M Kussmann, DH Abe Cunha, S Berciano - Frontiers in Nutrition, 2023 - frontiersin.org
Bioactive compounds found in edible plants and foods are vital for human and planetary
health, yet their significance remains underappreciated. These natural bioactives, as part of …

Predicting personalized responses to dietary fiber interventions: opportunities for modulation of the gut microbiome to improve health

CR Kok, D Rose, R Hutkins - Annual Review of Food Science …, 2023 - annualreviews.org
Inadequate dietary fiber consumption has become common across industrialized nations,
accompanied by changes in gut microbial composition and a dramatic increase in chronic …

Causal associations between human gut microbiota and cholelithiasis: a mendelian randomization study

W Li, A Ren, Q Qin, L Zhao, Q Peng, R Ma… - Frontiers in Cellular and …, 2023 - frontiersin.org
Background There was some evidence that gut microbiota was closely related to
cholelithiasis, but the causal relationship between them remained unclear. In this study, we …

Unveiling and harnessing the human gut microbiome in the rising burden of non-communicable diseases during urbanization

Z Huang, Y Li, H Park, M Ho, K Bhardwaj… - Gut …, 2023 - Taylor & Francis
The world is witnessing a global increase in the urban population, particularly in develo**
Asian and African countries. Concomitantly, the global burden of non-communicable …

Upper small intestine microbiome in obesity and related metabolic disorders: A new field of investigation

E Steinbach, D Masi, A Ribeiro, P Serradas, T Le Roy… - Metabolism, 2024 - Elsevier
The study of the gut microbiome holds great promise for understanding and treating
metabolic diseases, as its functions and derived metabolites can influence the metabolic …

Targeting gut-liver axis by dietary lignans ameliorate obesity: Evidences and mechanisms

Z Chu, Z Hu, Y Luo, Y Zhou, F Yang… - Critical reviews in food …, 2025 - Taylor & Francis
An imbalance between energy consumption and energy expenditure causes obesity. It is
characterized by increased adipose accumulation and accompanied by chronic low-grade …