Endogenous photosensitizers in human skin

EL Bastos, FH Quina, MS Baptista - Chemical Reviews, 2023 - ACS Publications
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation

J Cadet, JR Wagner - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
Emphasis has been placed in this article dedicated to DNA damage on recent aspects of the
formation and measurement of oxidatively generated damage in cellular DNA in order to …

Formation of UV-induced DNA damage contributing to skin cancer development

J Cadet, T Douki - Photochemical & Photobiological Sciences, 2018 - pubs.rsc.org
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

Quantum mechanical studies on the photophysics and the photochemistry of nucleic acids and nucleobases

R Improta, F Santoro, L Blancafort - Chemical reviews, 2016 - ACS Publications
The photophysics and photochemistry of DNA is of great importance due to the potential
damage of the genetic code by UV light. Quantum mechanical studies have played a key …

Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation,

J Cadet, T Douki, JL Ravanat - Photochemistry and …, 2015 - Wiley Online Library
This review article focuses on a critical survey of the main available information on the UVB
and UVA oxidative reactions to cellular DNA as the result of direct interactions of UV …

Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions

J Cadet, S Mouret, JL Ravanat… - Photochemistry and …, 2012 - Wiley Online Library
The survey focuses on recent aspects of photochemical reactions to cellular DNA that are
implicated through the predominant formation of mostly bipyrimidine photoproducts in …

Fundamentals of the intrinsic DNA fluorescence

T Gustavsson, D Markovitsi - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus The intrinsic fluorescence of nucleic acids is extremely weak compared to that
of the fluorescent labels used to probe their structural and functional behavior. Thus, for …

Molecular and physiological effects of environmental UV radiation on fungal conidia

GUL Braga, DEN Rangel, ÉKK Fernandes, SD Flint… - Current genetics, 2015 - Springer
Conidia are specialized structures produced at the end of the asexual life cycle of most
filamentous fungi. They are responsible for fungal dispersal and environmental persistence …

Solar UV radiation-induced DNA bipyrimidine photoproducts: formation and mechanistic insights

J Cadet, A Grand, T Douki - Photoinduced phenomena in nucleic acids II …, 2015 - Springer
This review chapter presents a critical survey of the main available information on the UVB
and UVA bipyrimidine photoproducts which constitute the predominant recipient classes of …

Standardized 3D bioprinting of soft tissue models with human primary cells

M Rimann, E Bono, H Annaheim… - Journal of …, 2016 - journals.sagepub.com
Cells grown in 3D are more physiologically relevant than cells cultured in 2D. To use 3D
models in substance testing and regenerative medicine, reproducibility and standardization …