Drug-discovery and drug-development endeavors are laborious, costly and time consuming.
These programs can take upward of 12 years and cost US $2.5 billion, with a failure rate of …

Natural products have been pivotal in treating mycobacterial infections with early antibiotics
such as streptomycin, forming the foundation of tuberculosis therapy. However, the …

With the rapid development of molecular sequencing and imaging technology, the multi-
omics of medicinal plants enters the single-cell era. We discuss spatial multi-omics applied …

Abstract Mimosa tenuiflora (" jurema-preta") is traditionally used in folk medicine for various
diseases. The study investigated the neuropharmacological potential of Mimosa tenuiflora …

For a long time, natural products (NP) contribute to the treatment of human pathologies,
notably to cancer treatment with microbial and plant-derived products. The mechanism of …

Milbemycins are a group of 16‐membered macrolides produced by the soil‐dwelling
filamentous bacteria Streptomyces. Renowned for their potent acaricidal and insecticidal …

A significant bottleneck in the discovery of novel antibiotics is the poor understanding of the
mechanism of action as it impedes compound prioritization for further development …

In the 21st century, the convergence of artificial intelligence (AI) and microbiology has
triggered a transformative era of bioprospecting. Microbial resources, long valued for their …

In the rapidly evolving landscape of genomics and biotechnology, the confluence of
metagenomics and artificial intelligence (AI) has ushered in a new era of scientific discovery …