Glutamate-gated chloride channels (GluCls) are found only in protostome invertebrate phyla
but are closely related to mammalian glycine receptors. They have a number of roles in …

GABA A receptors are ligand-gated ion channels composed of five subunits that can be
opened by GABA and be modulated by multiple pharmacologically and clinically important …

Anthelmintic resistance has a great impact on livestock production systems worldwide, is an
emerging concern in companion animal medicine, and represents a threat to our ongoing …

Chemogenetic technologies enable selective pharmacological control of specific cell
populations. An increasing number of approaches have been developed that modulate …

Strychnine-sensitive glycine receptors (GlyRs) mediate synaptic inhibition in the spinal cord,
brainstem, and other regions of the mammalian central nervous system. In this minireview …

Abstract Glycine Receptors (GlyRs) provide inhibitory neuronal input in the spinal cord and
brainstem, which is critical for muscle coordination and sensory perception. Synaptic GlyRs …

The frequent and extensive use of insecticides leads to the evolution of insecticide
resistance, which has become one of the constraints on global agricultural production …

High levels of resistance to spinosad, a macrocyclic lactone insecticide, have been reported
previously in western flower thrips, Frankliniella occidentalis, an economically important …

Ivermectin acts as a positive allosteric modulator of several Cys-loop receptors including the
glutamate-gated chloride channels (GluCls), γ-aminobutyric acid receptors (GABA A Rs) …

The RDL GABA receptor is an attractive target of insecticides. Here we demonstrate that
meta-diamides [3-benzamido-N-(4-(perfluoropropan-2-yl) phenyl) benzamides] are a distinct …