Mitochondria are essential for the viability of eukaryotic cells as they perform crucial
functions in bioenergetics, metabolism and signalling and have been associated with …

Biogenesis of mitochondria requires the import of approximately 1,000 different precursor
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …

Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling,
and their dysfunction has been linked to numerous diseases. The available studies cover …

Mitochondria are one of the most exhaustively investigated organelles in the cell and most
attention has been paid to the components of the mitochondrial electron transport chain …

Mitochondrial dysfunction is a hallmark of multiple metabolic complications. Physical activity
is known to increase mitochondrial content in skeletal muscle, counteracting age-related …

Mitochondria are central to cellular metabolism and energy conversion. In plants they also
enable photosynthesis through additional components and functional flexibility. A majority of …

Most proteins are organized in macromolecular assemblies, which represent key functional
units regulating and catalyzing most cellular processes. Affinity purification of the protein of …

The filtration of blood in the kidney which is crucial for mammalian life is determined by the
slit-diaphragm, a cell-cell junction between the foot processes of renal podocytes. The slit …

Mitochondria have crucial roles in cellular energetics, metabolism, signalling and quality
control,,–. They contain around 1,000 different proteins that often assemble into complexes …

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 …