[HTML][HTML] Alternatives to overcoming bacterial resistances: State-of-the-art

AC Rios, CG Moutinho, FC Pinto, FS Del Fiol… - Microbiological …, 2016 - Elsevier
Worldwide, bacterial resistance to chemical antibiotics has reached such a high level that
endangers public health. Presently, the adoption of alternative strategies that promote the …

[HTML][HTML] Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection

M Masomian, Z Ahmad, L Ti Gew, CL Poh - Vaccines, 2020 - mdpi.com
Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million
deaths annually, especially in young children and the elderly. To date, at least 98 different …

Fourteen years in resistance

DM Livermore - International journal of antimicrobial agents, 2012 - Elsevier
Resistance trends have changed greatly over the 14 years (1997–2011) whilst I was
Director of the UK Antibiotic Resistance Monitoring and Reference Laboratory (ARMRL) …

Impact and effectiveness of 10 and 13-valent pneumococcal conjugate vaccines on hospitalization and mortality in children aged less than 5 years in Latin American …

LH de Oliveira, LAB Camacho, ESF Coutinho… - PLoS one, 2016 - journals.plos.org
Background Several Latin American and Caribbean (LAC) countries have introduced
pneumococcal conjugate vaccine (PCV-10 or PCV-13) in their routine national immunization …

Prevention of pneumococcal diseases in the post-seven valent vaccine era: a European perspective

C Weil-Olivier, M van der Linden, I De Schutter… - BMC infectious …, 2012 - Springer
Background The burden of invasive pneumococcal disease in young children decreased
dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) …

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

JD Chalmers, J Campling, A Dicker… - BMC pulmonary …, 2016 - Springer
Background Invasive pneumococcal disease (IPD) and pneumococcal pneumonia are
common and carry a significant morbidity and mortality. Current strategies to prevent …

A novel of azo-thiazole moiety alternative for benzidine-based pigments: Design, synthesis, characterization, biological evaluation, and molecular docking study

HF Rizk, MA El-Borai, A Ragab… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A new series of coloring compounds (pigments) based on 5-(2-aminothiazol-5-yl) thiazol-2-
amine and 5-(4-aminophenyl) thiazol-2-amine as heterocyclic alternatives for benzidine …

Serotype-independent pneumococcal vaccines

EN Miyaji, MLS Oliveira, E Carvalho, PL Ho - Cellular and Molecular Life …, 2013 - Springer
Streptococcus pneumoniae remains an important cause of disease with high mortality and
morbidity, especially in children and in the elderly. The widespread use of the …

Glycoconjugate vaccines: an update

M Vella, D Pace - Expert opinion on biological therapy, 2015 - Taylor & Francis
Introduction: Globally, the three main pathogens causing serious infections are
Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis …

Polysaccharide-specific memory B cells predict protection against experimental human pneumococcal carriage

SH Pennington, S Pojar, E Mitsi, JF Gritzfeld… - American journal of …, 2016 - atsjournals.org
Rationale: We have previously demonstrated that experimental pneumococcal carriage
enhances immunity and protects healthy adults against carriage reacquisition after …