Tumor-on-a-chip: from bioinspired design to biomedical application
X Liu, J Fang, S Huang, X Wu, X **e, J Wang… - Microsystems & …, 2021 - nature.com
Cancer is one of the leading causes of human death, despite enormous efforts to explore
cancer biology and develop anticancer therapies. The main challenges in cancer research …
cancer biology and develop anticancer therapies. The main challenges in cancer research …
Three-dimensional cell cultures in drug discovery and development
Y Fang, RM Eglen - Slas discovery: Advancing Life Sciences …, 2017 - journals.sagepub.com
The past decades have witnessed significant efforts toward the development of three-
dimensional (3D) cell cultures as systems that better mimic in vivo physiology. Today, 3D …
dimensional (3D) cell cultures as systems that better mimic in vivo physiology. Today, 3D …
Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
P Zamprogno, S Wüthrich, S Achenbach… - Communications …, 2021 - nature.com
The air-blood barrier with its complex architecture and dynamic environment is difficult to
mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin …
mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin …
Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
3D printing: an emerging tool for novel microfluidics and lab-on-a-chip applications
In the past few years, 3D printing technology has witnessed an explosive growth,
penetrating various aspects of our lives. Current best-in-class 3D printers can fabricate …
penetrating various aspects of our lives. Current best-in-class 3D printers can fabricate …
3D printing techniques and their applications to organ-on-a-chip platforms: a systematic review
Three-dimensional (3D) in vitro models, such as organ-on-a-chip platforms, are an emerging
and effective technology that allows the replication of the function of tissues and organs …
and effective technology that allows the replication of the function of tissues and organs …
Electrical and mechanical stimulation of cardiac cells and tissue constructs
The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …
decades, highlighted by the development of human cell derived constructs that have shown …
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels
This paper reports a method for generating an intact and perfusable microvascular network
that connects to microfluidic channels without appreciable leakage. This platform …
that connects to microfluidic channels without appreciable leakage. This platform …
Dielectrophoresis for biomedical sciences applications: A review
Dielectrophoresis (DEP) is a label-free, accurate, fast, low-cost diagnostic technique that
uses the principles of polarization and the motion of bioparticles in applied electric fields …
uses the principles of polarization and the motion of bioparticles in applied electric fields …
Medium throughput breathing human primary cell alveolus-on-chip model
JD Stucki, N Hobi, A Galimov, AO Stucki… - Scientific reports, 2018 - nature.com
Organs-on-chips have the potential to improve drug development efficiency and decrease
the need for animal testing. For the successful integration of these devices in research and …
the need for animal testing. For the successful integration of these devices in research and …