Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023‏ - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection

LCK Bell, M Noursadeghi - Nature Reviews Microbiology, 2018‏ - nature.com
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …

Tuberculosis and HIV coinfection

J Bruchfeld, M Correia-Neves… - Cold Spring …, 2015‏ - perspectivesinmedicine.cshlp.org
Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency
syndrome (HIV/AIDS) constitute the main burden of infectious disease in resource-limited …

Tuberculosis and HIV co-infection

A Pawlowski, M Jansson, M Sköld… - PLoS …, 2012‏ - journals.plos.org
Tuberculosis (TB) and HIV co-infections place an immense burden on health care systems
and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most …

HIV and tuberculosis: a deadly human syndemic

CK Kwan, JD Ernst - Clinical microbiology reviews, 2011‏ - journals.asm.org
SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

[HTML][HTML] Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2

L Petrone, E Petruccioli, V Vanini, G Cuzzi… - International journal of …, 2021‏ - Elsevier
Objectives The interaction of COVID-19 and tuberculosis (TB) are still poor characterized.
Here we evaluated the immune response specific for Micobacterium tuberculosis (Mtb) and …

Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents

RS Keri, BS Sasidhar, BM Nagaraja… - European journal of …, 2015‏ - Elsevier
Tuberculosis (TB) is still a challenging worldwide health problem and mycobacterium
tuberculosis (MTB) remains one of the most deadly human pathogens. TB is the second …

Treatment of latent tuberculosis infection in HIV infected persons

C Akolo, I Adetifa, S Shepperd… - Cochrane database of …, 2010‏ - cochranelibrary.com
Background Individuals with human immunodeficiency virus (HIV) infection are at an
increased risk of develo** active tuberculosis (TB). It is known that treatment of latent TB …

Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis

E Petruccioli, TJ Scriba, L Petrone… - European …, 2016‏ - publications.ersnet.org
New approaches to control the spread of tuberculosis (TB) are needed, including tools to
predict development of active TB from latent TB infection (LTBI). Recent studies have …

HIV/Mtb co-infection: from the amplification of disease pathogenesis to an “emerging syndemic”

JM Azevedo-Pereira, D Pires, M Calado, M Mandal… - Microorganisms, 2023‏ - mdpi.com
Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are pathogens
responsible for millions of new infections each year; together, they cause high morbidity and …