Hydrogels are polymeric three-dimensional network structures with high water content. Due
to their superior biocompatibility and low toxicity, hydrogels play a significant role in the …

It is widely accepted that three-dimensional cell culture systems simulate physiological
conditions better than traditional 2D systems. Although extracellular matrix components …

Hydrogel physical properties are tuned by altering synthesis conditions such as initial
polymer concentration and polymer–cross-linker stoichiometric ratios. Traditionally …

Due to their particular water absorption capacity, hydrogels are the most widely used
scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in …

The main objective of this review is to provide a comprehensive overview of the current
evidence regarding the use of chitosan-based hydrogels to manage skin infections …

Cells sense mechanical cues from the extracellular matrix to regulate cellular behavior and
maintain tissue homeostasis. The nucleus has been implicated as a key mechanosensor …

Mechanical cues from the extracellular matrix (ECM) microenvironment are known to be
significant in modulating the fate of stem cells to guide developmental processes and …

Nearly all cardiovascular diseases show sexual dimorphisms in prevalence, presentation,
and outcomes. Until recently, most clinical trials were carried out in males, and many animal …

The extracellular matrix (ECM) of natural cells typically exhibits dynamic mechanical
properties (viscoelasticity and dynamic stiffness). The viscoelasticity and dynamic stiffness of …

In vitro cardiac modeling has taken great strides in the past decade. While most cell and
engineered tissue models have focused on cell and tissue contractile function as readouts …