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Autoantibodies in neurological disease
H Prüss - Nature reviews immunology, 2021 - nature.com
The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …
about a paradigm shift in neurological diseases over the past decade, offering up important …
Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
The importance of early immunotherapy in patients with faciobrachial dystonic seizures
Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to
leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with …
leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with …
Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis
MAAM de Bruijn, A van Sonderen… - Neurology, 2019 - neurology.org
Objective This nationwide cohort study evaluates seizure responses to immunotherapy and
antiepileptic drugs (AEDs) in patients with anti-leucine-rich glioma-inactivated 1 (LGI1), anti …
antiepileptic drugs (AEDs) in patients with anti-leucine-rich glioma-inactivated 1 (LGI1), anti …
Treatment strategies for autoimmune encephalitis
YW Shin, ST Lee, KI Park, KH Jung… - Therapeutic …, 2018 - journals.sagepub.com
Autoimmune encephalitis is one of the most rapidly growing research topics in neurology.
Along with discoveries of novel antibodies associated with the disease, clinical experience …
Along with discoveries of novel antibodies associated with the disease, clinical experience …
The value of LGI1, Caspr2 and voltage-gated potassium channel antibodies in encephalitis
The discovery, in 2010, of autoantibodies against the extracellular proteins LGI1 and Caspr2
facilitated a change of view regarding the clinical importance of voltage-gated potassium …
facilitated a change of view regarding the clinical importance of voltage-gated potassium …
[HTML][HTML] Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank
Measurement of hippocampal volume has proven useful to diagnose and track progression
in several brain disorders, most notably in Alzheimer's disease (AD). For example, an …
in several brain disorders, most notably in Alzheimer's disease (AD). For example, an …
LGI1 antibody encephalitis: acute treatment comparisons and outcome
A Rodriguez, CJ Klein, E Sechi, E Alden… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective To compare acute treatment responses and long-term outcome in leucine-rich
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …
Prognosticating autoimmune encephalitis: a systematic review
Objective To perform a systematic review of the current scientific literature in order to identify
variables associated with patient prognosis in autoimmune encephalitis. Methods We …
variables associated with patient prognosis in autoimmune encephalitis. Methods We …
LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes
Recent biochemical observations have helped redefine antigenic components within the
voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now …
voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now …