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Extracellular vesicles as biomarkers and therapeutic targets for cancer
Extracellular vesicles (EVs) are small lipid membrane vesicles that are secreted from almost
all kinds of cells into the extracellular space. EVs are widely accepted to be involved in …
all kinds of cells into the extracellular space. EVs are widely accepted to be involved in …
Oxidative stress in drug-induced liver injury (DILI): from mechanisms to biomarkers for use in clinical practice
M Villanueva-Paz, L Morán, N López-Alcántara… - Antioxidants, 2021 - mdpi.com
Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an
uncommon drug adverse reaction that can develop to conditions spanning from …
uncommon drug adverse reaction that can develop to conditions spanning from …
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
L Cheng, RA Sharples, BJ Scicluna… - Journal of extracellular …, 2014 - Taylor & Francis
Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …
processed in the host cell and released extracellularly into the bloodstream. Normally …
Circulating exosomal microRNAs as biomarkers of colon cancer
H Ogata-Kawata, M Izumiya, D Kurioka, Y Honma… - PloS one, 2014 - journals.plos.org
Purpose Exosomal microRNAs (miRNAs) have been attracting major interest as potential
diagnostic biomarkers of cancer. The aim of this study was to characterize the miRNA …
diagnostic biomarkers of cancer. The aim of this study was to characterize the miRNA …
Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non–small cell lung cancer using next-generation sequencing
X **, Y Chen, H Chen, S Fei, D Chen, X Cai… - Clinical cancer …, 2017 - aacrjournals.org
Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …
Non-exosomal and exosomal circulatory microRNAs: which are more valid as biomarkers?
NNSB Nik Mohamed Kamal… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …
nucleotides that are involved in regulating a range of developmental and physiological …
An elevated expression of serum exosomal microRNA-191,− 21,− 451a of pancreatic neoplasm is considered to be efficient diagnostic marker
T Goto, M Fujiya, H Konishi, J Sasajima, S Fujibayashi… - BMC cancer, 2018 - Springer
Background Pancreatic cancer is associated with an extremely poor prognosis, so new
biomarkers that can detect the initial stages are urgently needed. The significance of serum …
biomarkers that can detect the initial stages are urgently needed. The significance of serum …
Circulating microRNAs as potential biomarkers of infectious disease
CN Correia, NC Nalpas, KE McLoughlin… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that
regulate a wide range of biological processes by post-transcriptionally regulating gene …
regulate a wide range of biological processes by post-transcriptionally regulating gene …
Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR
The high-throughput analysis of microRNAs (miRNAs) circulating within the blood of healthy
and diseased individuals is an active area of biomarker research. Whereas quantitative real …
and diseased individuals is an active area of biomarker research. Whereas quantitative real …
[HTML][HTML] Impact of storage conditions on EV integrity/surface markers and cargos
Extracellular vesicles (EVs) are small biological particles released into biofluids by every
cell. Based on their size, they are classified into small EVs (< 100 nm or< 200 nm) and …
cell. Based on their size, they are classified into small EVs (< 100 nm or< 200 nm) and …