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Secretion of pro-oncogenic AGR2 protein in cancer
Abstract Anterior gradient-2 (AGR2) protein mediates the formation, breakage and
isomerization of disulphide bonds during protein maturation in the endoplasmic reticulum …
isomerization of disulphide bonds during protein maturation in the endoplasmic reticulum …
The prognostic value of AGR2 expression in solid tumours: a systematic review and meta-analysis
S Tian, K Tao, J Hu, Z Liu, X Ding, Y Chu, J Cui… - Scientific reports, 2017 - nature.com
The prognostic value of anterior gradient-2 (AGR2) in tumours remains inconclusive. Here,
we systematically reviewed the literature evidence and assessed the association between …
we systematically reviewed the literature evidence and assessed the association between …
Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture
F Grillet, E Bayet, O Villeronce, L Zappia, EL Lagerqvist… - Gut, 2017 - gut.bmj.com
Objective Although counting of circulating tumour cells (CTC) has attracted a broad interest
as potential markers of tumour progression and treatment response, the lack of functional …
as potential markers of tumour progression and treatment response, the lack of functional …
miR-342-3p suppresses cell proliferation and migration by targeting AGR2 in non-small cell lung cancer
X Xue, X Fei, W Hou, Y Zhang, L Liu, R Hu - Cancer letters, 2018 - Elsevier
AGR2 is a well-studied secreted protein that is involved in multiple biological processes
including cell proliferation and migration. The mechanism by which AGR2 increases the …
including cell proliferation and migration. The mechanism by which AGR2 increases the …
Identification of novel gene expression signature in lung adenocarcinoma by using next-generation sequencing data and bioinformatics analysis
YL Hsu, JY Hung, YL Lee, FW Chen, KF Chang… - …, 2017 - pmc.ncbi.nlm.nih.gov
Lung adenocarcinoma is one of the leading causes of cancer-related death worldwide. We
showed transcriptomic profiles in three pairs of tumors and adjacent non-tumor lung tissues …
showed transcriptomic profiles in three pairs of tumors and adjacent non-tumor lung tissues …
[HTML][HTML] FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas
Lung cancer remains one of the most prominent public health challenges, accounting for the
highest incidence and mortality among all human cancers. While pulmonary invasive …
highest incidence and mortality among all human cancers. While pulmonary invasive …
Unraveling the impact of cancer-associated fibroblasts on hypovascular pancreatic neuroendocrine tumors
TY Lai, TC Chiang, CY Lee, TC Kuo, CH Wu… - British Journal of …, 2024 - nature.com
Abstract Background Pancreatic neuroendocrine tumors (PNETs) with low microvessel
density and fibrosis often exhibit clinical aggressiveness. Given the contribution of cancer …
density and fibrosis often exhibit clinical aggressiveness. Given the contribution of cancer …
Distinct signatures of lung cancer types: aberrant mucin O-glycosylation and compromised immune response
M Lucchetta, I da Piedade, M Mounir, M Vabistsevits… - BMC cancer, 2019 - Springer
Background Genomic initiatives such as The Cancer Genome Atlas (TCGA) contain data
from-omics profiling of thousands of tumor samples, which may be used to decipher cancer …
from-omics profiling of thousands of tumor samples, which may be used to decipher cancer …
From development to cancer-an ever-increasing role of AGR2
D Jach, Y Cheng, F Prica, L Dumartin… - American journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Anterior gradient 2, AGR2, is a small, 20 kDa protein that plays a vital role in oxidative
protein folding in the endoplasmic reticulum. AGR2 is involved in several signal transduction …
protein folding in the endoplasmic reticulum. AGR2 is involved in several signal transduction …
[HTML][HTML] Prostate cancer research: tools, cell types, and molecular targets
AY Liu - Frontiers in Oncology, 2024 - frontiersin.org
Multiple cancer cell types are found in prostate tumors. They are either luminal-like
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …