Genome-wide association studies (GWAS) provide an important avenue for undertaking an
agnostic evaluation of the association between common genetic variants and risk of …

Pooled Association Tests for Rare Genetic Variants: A Review and Some New Results. The
supplementary materials include derivation of the permutation distribution of S for general …

Missing data occur in genetic association studies for several reasons including missing
family members and uncertain haplotype phase. Maximum likelihood is a commonly used …

Endophenotypes or intermediate phenotypes are of great interest in neuropsychiatric
genetics because of their potential for facilitating gene discovery. We evaluated response …

Variants identified in recent genome‐wide association studies based on the common‐
disease common‐variant hypothesis are far from fully explaining the hereditability of …

Provides cutting edge coverage of current gene map** approaches grounded in a
traditional statistical genetics framework, with emphasis on association studies Provides …

In the increasing number of sequencing studies aimed at identifying rare variants associated
with complex traits, the power of the test can be improved by guided sampling procedures …

Background Thirty-two common variants associated with body mass index (BMI) have been
identified in genome-wide association studies, explaining∼ 1.45% of BMI variation in …

Central corneal thickness (CCT), one of the most highly heritable human traits (h2 typically>
0.9), is important for the diagnosis of glaucoma and a potential risk factor for glaucoma …

Using a moderate‐sized cohort selected with extreme BMD (n= 344; absolute value BMD,
1.5–4.0), significant association of several members of the Wnt signaling pathway with bone …