Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives

S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

Tumor microenvironment complexity and therapeutic implications at a glance

R Baghban, L Roshangar… - Cell Communication and …, 2020 - Springer
The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …

Surface plasmon resonance (SPR) sensor for cancer biomarker detection

S Das, R Devireddy, MR Gartia - Biosensors, 2023 - mdpi.com
A biomarker is a physiological observable marker that acts as a stand-in and, in the best-
case scenario, forecasts a clinically significant outcome. Diagnostic biomarkers are more …

[HTML][HTML] Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer

P Kumar, S Gupta, BC Das - Translational oncology, 2024 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …

Next-generation sequencing in liquid biopsy: cancer screening and early detection

M Chen, H Zhao - Human genomics, 2019 - Springer
In recent years, the rapid development of next-generation sequencing (NGS) technologies
has led to a significant reduction in sequencing cost with improved accuracy. In the area of …

[HTML][HTML] Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

[HTML][HTML] How liquid biopsies can change clinical practice in oncology

G Siravegna, B Mussolin, T Venesio, S Marsoni… - Annals of …, 2019 - Elsevier
Cell-free DNA fragments are shed into the bloodstream by tumor cells. The analysis of
circulating tumor DNA (ctDNA), commonly known as liquid biopsy, can be exploited for a …

[PDF][PDF] Next-generation sequencing and its clinical application

D Qin - Cancer biology & medicine, 2019 - cancerbiomed.org
Next-generation sequencing (NGS) is a new technology used for DNA and RNA sequencing
and variant/mutation detection. NGS can sequence hundreds and thousands of genes or …

Advances in surface plasmon resonance–based biosensor technologies for cancer biomarker detection

A Azzouz, L Hejji, KH Kim, D Kukkar, B Souhail… - Biosensors and …, 2022 - Elsevier
Surface plasmon resonance approach is a highly useful option to offer optical and label-free
detection of target bioanalytes with numerous advantages (eg, low-cost fabrication …

Recent advances and emerging trends in cancer biomarker detection technologies

RR Kumar, A Kumar, CH Chuang… - Industrial & Engineering …, 2023 - ACS Publications
Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …