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Towards a deeper understanding of the vaginal microbiota
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …
live in close association with the vaginal epithelium and rely on host tissues for resources …
Vaginal microbiome: normalcy vs dysbiosis
It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …
physiological environment for the host and its involvement is deemed indispensable for …
The vaginal microbiome and preterm birth
The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in
the frequency of preterm birth among populations within countries, and women of African …
the frequency of preterm birth among populations within countries, and women of African …
The vaginal microbiome and the risk of preterm birth: a systematic review and network meta-analysis
Preterm birth is a major cause of neonatal morbidity and mortality worldwide. Increasing
evidence links the vaginal microbiome to the risk of spontaneous preterm labour that leads …
evidence links the vaginal microbiome to the risk of spontaneous preterm labour that leads …
Interferons and proinflammatory cytokines in pregnancy and fetal development
Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …
[HTML][HTML] The central nervous system and the gut microbiome
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …
While historically studied by researching the brain, inputs from the periphery impact many …
Cervicovaginal microbiota and local immune response modulate the risk of spontaneous preterm delivery
MA Elovitz, P Gajer, V Riis, AG Brown… - Nature …, 2019 - nature.com
Failure to predict and understand the causes of preterm birth, the leading cause of neonatal
morbidity and mortality, have limited effective interventions and therapeutics. From a cohort …
morbidity and mortality, have limited effective interventions and therapeutics. From a cohort …
Evidence that the endometrial microbiota has an effect on implantation success or failure
Background Bacterial cells in the human body account for 1–3% of total body weight and are
at least equal in number to human cells. Recent research has focused on understanding …
at least equal in number to human cells. Recent research has focused on understanding …
Risk factors for spontaneous preterm delivery
T Cobo, M Kacerovsky… - International Journal of …, 2020 - Wiley Online Library
Background There is a substantial variation in rates of preterm delivery between different
parts of the world. The understanding of these variations, as well as the biological …
parts of the world. The understanding of these variations, as well as the biological …
Replication and refinement of a vaginal microbial signature of preterm birth in two racially distinct cohorts of US women
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Previous
studies have suggested that the maternal vaginal microbiota contributes to the …
studies have suggested that the maternal vaginal microbiota contributes to the …