This critical review presents an introduction to biocatalysis for synthetic chemists. Advances
in biocatalysis of the past 5 years illustrate the breadth of applications for these powerful and …

This review outlines the most recent papers describing the stereoselective synthesis of γ-
amino acids. In this update, the γ-amino acids have been classified according to the type of …

The use of halogen bond is widespread in drug discovery, design, and clinical trials, but is
overlooked in drug biosynthesis. Here, the role of halogen bond in the nitrilase-catalyzed …

The range of possible nitrilase applications has been recently broadened but in most cases
the parameters of the reactions need to be improved to establish viable industrial processes …

Abstract γ‐Amino esters and γ‐lactams containing α, γ‐stereogenic centers are widely used
as chiral intermediates in various bioactive compounds, while their efficient synthesis …

A high‐throughput screening of candidate nitrilases against 25 structurally diverse
substrates allowed us to create a wide collection of 125 experimentally validated nitrilases …

By adopting green chemistry principles and methodologies, researchers can devise new
processes to help protect the environment from further damage. In this book, eminent …

Of the numerous putative fungal nitrilases available from protein databases only a few
enzymes were purified and characterized. The purified nitrilases from Fusarium solani …

Several biocatalytic approaches for the preparation of optically pure methyl 3-
oxocyclohexanecarboxylates (S)-,(R)-1 and 3-oxocyclohexanecarbonitriles (S)-,(R)-2 have …

Baker's yeast and Old Yellow Enzyme-mediated reduction of the carbon–carbon double
bonds of β-cyano-α, β-unsaturated esters was investigated, in order to broaden the …