The role of platelets in immune-mediated inflammatory diseases

M Scherlinger, C Richez, GC Tsokos… - Nature Reviews …, 2023 - nature.com
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …

The dynamic role of platelets in cancer progression and their therapeutic implications

S Li, Z Lu, S Wu, T Chu, B Li, F Qi, Y Zhao… - Nature Reviews Cancer, 2024 - nature.com
Systemic antiplatelet treatment represents a promising option to improve the therapeutic
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …

The impact of COVID-19 disease on platelets and coagulation

GD Wool, JL Miller - Pathobiology, 2021 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some
patients develop a severe proinflammatory state which can be associated with a unique …

The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases

L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis

B Wei, C Sun, H Wan, Q Shou, B Han, M Sheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge (SM) is an outstanding
herbal medicine with various traditional effects, especially promoting blood circulation to …

The life cycle of platelet granules

A Sharda, R Flaumenhaft - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
Platelet granules are unique among secretory vesicles in both their content and their life
cycle. Platelets contain three major granule types—dense granules, α-granules, and …

Superhydrophobic blood‐repellent surfaces

V Jokinen, E Kankuri, S Hoshian, S Franssila… - Advanced …, 2018 - Wiley Online Library
Superhydrophobic surfaces repel water and, in some cases, other liquids as well. The
repellency is caused by topographical features at the nano‐/microscale and low surface …

Sepsis–it is all about the platelets

D Cox - Frontiers in immunology, 2023 - frontiersin.org
Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation

SN Randeria, GJA Thomson, TA Nell, T Roberts… - Cardiovascular …, 2019 - Springer
Background The global burden of type 2 diabetes mellitus (T2DM), together with the
presence of cardiovascular risk in this population, is reaching pandemic levels. A prominent …

[HTML][HTML] Platelet function, role in thrombosis, inflammation, and consequences in chronic myeloproliferative disorders

L Repsold, AM Joubert - Cells, 2021 - mdpi.com
Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis.
This role has over the years transformed as knowledge regarding platelets has expanded to …