Serial sampling of serum protein biomarkers for monitoring human traumatic brain injury dynamics: a systematic review
Background The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …
Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …
modulated transcription factor that governs the expression of genes involved in …
S100B in brain damage and neurodegeneration
M Rothermundt, M Peters, JHM Prehn… - … research and technique, 2003 - Wiley Online Library
S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …
Erythropoietin therapy for acute stroke is both safe and beneficial
H Ehrenreich, M Hasselblatt, C Dembowski, L Cepek… - Molecular …, 2002 - Springer
Background Erythropoietin (EPO) and its receptor play a major role in embryonic brain, are
weakly expressed in normal postnatal/adult brain and up-regulated upon metabolic stress …
weakly expressed in normal postnatal/adult brain and up-regulated upon metabolic stress …
The S100B protein in biological fluids: more than a lifelong biomarker of brain distress
J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …
Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment
AK Saenger, RH Christenson - Clinical chemistry, 2010 - academic.oup.com
Background: Stroke is a devastating condition encompassing a wide range of
pathophysiological entities that include thrombosis, hemorrhage, and embolism. Current …
pathophysiological entities that include thrombosis, hemorrhage, and embolism. Current …
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study
Y Tang, H Xu, XL Du, L Lit, W Walker… - Journal of Cerebral …, 2006 - journals.sagepub.com
Ischemic brain and peripheral white blood cells release cytokines, chemokines and other
molecules that activate the peripheral white blood cells after stroke. To assess gene …
molecules that activate the peripheral white blood cells after stroke. To assess gene …
Serum neuron-specific enolase and S-100B protein in cardiac arrest patients treated with hypothermia
M Tiainen, RO Roine, V Pettilä, O Takkunen - Stroke, 2003 - Am Heart Assoc
Background and Purpose—High serum levels of neuron-specific enolase (NSE) and S-100B
protein are known to be associated with ischemic brain injury and poor outcome after …
protein are known to be associated with ischemic brain injury and poor outcome after …
Blood biomarkers for detection of brain injury in COVID-19 patients
ST DeKosky, PM Kochanek, AB Valadka… - Journal of …, 2021 - liebertpub.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus attacks multiple
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …
S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury
As an astrocytic protein specific to the central nervous system, S100b is a potentially useful
marker in outcome prediction after traumatic brain injury (TBI). Some studies have …
marker in outcome prediction after traumatic brain injury (TBI). Some studies have …