Serovars of Salmonella enterica cause both gastrointestinal and systemic diseases in a
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …

Foodborne pathogens, mostly bacteria and fungi, but also some viruses, prions and
protozoa, contaminate food during production and processing, but also during storage and …

Ubiquitylation is a crucial post-translational protein modification that regulates several
cellular processes in eukaryotes, including inflammatory responses, endocytic trafficking …

Intracellular bacterial pathogens inject effector proteins to hijack host cellular processes and
promote their survival and proliferation. To systematically map effector-host protein-protein …

Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …

Intracellular bacterial pathogens hijack the protein machinery of infected host cells to evade
their defenses and cultivate a favorable intracellular niche. The intracellular pathogen …

Elucidation of molecular mechanisms underlying host-pathogen interactions is important for
control and treatment of infectious diseases worldwide. Within the last decade, mass …

Protein phosphorylation regulates a large variety of biological processes in all living cells. In
pathogenic bacteria, the study of serine, threonine, and tyrosine (Ser/Thr/Tyr) …

The intracellular bacterial pathogen Legionella pneumophila utilizes the Dot/Icm system to
translocate over 330 effectors into the host cytosol. These virulence factors modify a variety …

Salmonella is a foodborne pathogen that predominantly resides in the intestinal tract of
humans and animals. Infections caused by Salmonella can lead to various illnesses …