Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …
evidence supplemented by expert clinical consensus and formulate recommendations to …
Cortisol and major depressive disorder—translating findings from humans to animal models and back
Major depressive disorder (MDD) is a global problem for which current pharmacotherapies
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
Depression and risk of develo** dementia
AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …
Depression has been linked with dementia, and growing evidence implies that the timing of …
A meta-analysis of cognitive deficits in first-episode major depressive disorder
BACKGROUND: Recurrent-episode Major Depressive Disorder (MDD) is associated with a
number of neuropsychological deficits. To date, less is known about whether these are …
number of neuropsychological deficits. To date, less is known about whether these are …
Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder
MJ Kempton, Z Salvador, MR Munafò… - Archives of general …, 2011 - jamanetwork.com
Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?
Major depressive disorder (MDD) has until recently been conceptualized as an episodic
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …
Brain volume abnormalities in major depressive disorder: A meta‐analysis of magnetic resonance imaging studies
Objective. So far, there have been no attempts to integrate the growing number of all brain
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …
Magnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analyses
Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-
cortical abnormalities in unipolar depression. However, the presence of duplicate …
cortical abnormalities in unipolar depression. However, the presence of duplicate …
Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions
Diagnosis in psychiatry increasingly struggles to fulfil its key purposes, namely, to guide
treatment and to predict outcome. The clinical staging model, widely used in clinical …
treatment and to predict outcome. The clinical staging model, widely used in clinical …