Spectral imaging is a technology that integrates conventional imaging and spectroscopy to
get both spatial and spectral information from an object. Although this technology was …

Background: Spectral imaging extends the capabilities of biological and clinical studies to
simultaneously study multiple features such as organelles and proteins qualitatively and …

In biological microscopy, the ever expanding range of applications requires quantitative
approaches that analyze several distinct fluorescent molecules at the same time in the same …

Multicolor fluorescence microscopy has become a popular way to discriminate between
multiple proteins, organelles, or functions in a single cell or animal and can be used to …

Fluorescence microscopy is an essential tool for modern biological research. The wide
range of available fluorophores and labeling techniques allows the creation of increasingly …

Background The usefulness of the light microscope has been dramatically enhanced by
recent developments in hardware and software. However, current technologies lack the …

Seven-color analyses of immunofluorescence-stained tissue samples were accomplished
using Fourier spectroscopy-based hyperspectral imaging and singular value decomposition …

The intracellular fate of particulate drug delivery systems is determined by the initial mode of
internalization and the subsequent intracellular trafficking. Besides clathrin-mediated …

Cytogenetic analysis provides critical information of diagnostic and prognostic importance
for haematological malignancies1, 2. In fact, the identification of recurring chromosomal …

Murine models of human carcinogenesis are exceedingly valuable tools to understand
genetic mechanisms of neoplastic growth. The identification of recurrent chromosomal …