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Recent aspects of the effects of zinc on human health
Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …
is involved in numerous biological functions and it is considered as a multipurpose trace …
[HTML][HTML] Zinc as a gatekeeper of immune function
I Wessels, M Maywald, L Rink - Nutrients, 2017 - mdpi.com
After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …
for the function of the immune system. Zinc ions are involved in regulating intracellular …
[HTML][HTML] Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism
A number of studies have reported that zinc plays a substantial role in the development of
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
metabolic syndrome, taking part in the regulation of cytokine expression, suppressing …
Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases
S Choi, X Liu, Z Pan - Acta Pharmacologica Sinica, 2018 - nature.com
Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …
inflammatory functions. The association between zinc deficiency and the development of …
Zinc transporters and their functional integration in mammalian cells
Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …
[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism
T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
[HTML][HTML] Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis
T Hara, T Takeda, T Takagishi, K Fukue… - The Journal of …, 2017 - Elsevier
Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …
The functions of metallothionein and ZIP and ZnT transporters: an overview and perspective
T Kimura, T Kambe - International journal of molecular sciences, 2016 - mdpi.com
Around 3000 proteins are thought to bind zinc in vivo, which corresponds to~ 10% of the
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …
[HTML][HTML] Nonalcoholic fatty liver disease and the gut-liver axis: exploring an undernutrition perspective
Nonalcoholic fatty liver disease (NAFLD) is a chronic condition affecting one quarter of the
global population. Although primarily linked to obesity and metabolic syndrome …
global population. Although primarily linked to obesity and metabolic syndrome …
The use of animal models in diabetes research
AJF King - British journal of pharmacology, 2012 - Wiley Online Library
Diabetes is a disease characterized by a relative or absolute lack of insulin, leading to
hyperglycaemia. There are two main types of diabetes: type 1 diabetes and type 2 diabetes …
hyperglycaemia. There are two main types of diabetes: type 1 diabetes and type 2 diabetes …