Associations between cells and the basement membrane are critical for a variety of
biological events including cell proliferation, cell migration, cell differentiation and the …

The agents causing viral hemorrhagic fever (VHF) are a taxonomically diverse group of
viruses that may share commonalities in the process whereby they produce systemic and …

To take complete advantage of information on within-species polymorphism and divergence
from close relatives, one needs to know the rate and the molecular spectrum of spontaneous …

Lujo virus (LUJV), a new member of the family Arenaviridae and the first hemorrhagic fever–
associated arenavirus from the Old World discovered in three decades, was isolated in …

Lassa virus (LASV) is a human pathogen, causing substantial morbidity and mortality,.
Similar to other Arenaviridae, it presents a class-I spike complex on its surface that facilitates …

At least five arenaviruses cause viral haemorrhagic fevers in humans. Lassa virus, an Old
World arenavirus, uses the cellular receptor α-dystroglycan to infect cells. Machupo …

Highlights•Most mammalian virus families use cell-surface glycans as receptors.•Glycan
receptors are diverse in structure and distribution, giving rise to species and tissue …

Alpha-dystroglycan (α-DG) is a cell-surface glycoprotein that acts as a receptor for both
extracellular matrix proteins containing laminin-G domains and certain arenaviruses …

Lassa virus is a RNA virus belonging to the family of Arenaviridae. It was discovered as the
causative agent of a hemorrhagic fever—Lassa fever—about 30 years ago. Lassa fever is …

The envelope glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV) is
posttranslationally cleaved into two subunits. We show here that this endoproteolytic …