Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
Unlocking the promise of mRNA therapeutics
E Rohner, R Yang, KS Foo, A Goedel… - Nature biotechnology, 2022 - nature.com
The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19)
has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical …
has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical …
The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
Biosystem‐inspired engineering of nanozymes for biomedical applications
L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia
Bioinspired microrobots capable of actively moving in biological fluids have attracted
considerable attention for biomedical applications because of their unique dynamic features …
considerable attention for biomedical applications because of their unique dynamic features …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Type-I AIE photosensitizer loaded biomimetic system boosting cuproptosis to inhibit breast cancer metastasis and rechallenge
Cuproptosis shows good application prospects in tumor therapy. However, the copper efflux
mechanism and highly expressed intracellular reducing substances can inhibit the …
mechanism and highly expressed intracellular reducing substances can inhibit the …
[HTML][HTML] Lipid nanoparticles for mRNA delivery
Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent
and treat various diseases. To function in vivo, mRNA requires safe, effective and stable …
and treat various diseases. To function in vivo, mRNA requires safe, effective and stable …
Aggregation‐induced emission‐based macrophage‐like nanoparticles for targeted photothermal therapy and virus transmission blockage in Monkeypox
B Li, W Wang, L Zhao, M Li, D Yan, X Li… - Advanced …, 2024 - Wiley Online Library
The recent prevalence of monkeypox has led to the declaration of a Public Health
Emergency of International Concern. Monkeypox lesions are typically ulcers or pustules …
Emergency of International Concern. Monkeypox lesions are typically ulcers or pustules …