[HTML][HTML] Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity

WAJ Vints, O Levin, H Fujiyama, J Verbunt… - Frontiers in …, 2022 - Elsevier
Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

[HTML][HTML] Understanding the neurophysiological and molecular mechanisms of exercise-induced neuroplasticity in cortical and descending motor pathways: where do …

C Nicolini, M Fahnestock, MJ Gibala, AJ Nelson - Neuroscience, 2021 - Elsevier
Exercise is a promising, cost-effective intervention to augment successful aging and
neurorehabilitation. Decline of gray and white matter accompanies physiological aging and …

Effects of aerobic exercise training on systemic biomarkers and cognition in late middle-aged adults at risk for Alzheimer's disease

JM Gaitán, HY Moon, M Stremlau, DB Dubal… - Frontiers in …, 2021 - frontiersin.org
Increasing evidence indicates that physical activity and exercise training may delay or
prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can …

Effects of a 12-week Vivifrail exercise program on intrinsic capacity among frail cognitively impaired community-dwelling older adults: secondary analysis of a …

JL Sánchez-Sánchez, P de Souto Barreto… - Age and …, 2022 - academic.oup.com
Abstract Introduction The World Health Organisation recently defined the construct of
intrinsic capacity (IC), a function-based marker of older adult's health encompassing all …

Acute increases in brain-derived neurotrophic factor in plasma following physical exercise relates to subsequent learning in older adults

J Nilsson, Ö Ekblom, M Ekblom, A Lebedev… - Scientific reports, 2020 - nature.com
Multidomain lifestyle interventions represents a promising strategy to counteract cognitive
decline in older age. Brain-derived neurotrophic factor (BDNF) is essential for experience …

[HTML][HTML] Exercise regulates myokines in Aging-related diseases through Muscle-Brain Crosstalk

B Wang, J Liang, C Lu, A Lu, C Wang - Gerontology, 2024 - karger.com
Background: The related functions of skeletal muscle and brain decrease significantly with
age, and muscle-brain-related diseases are primarily associated with each other. Exercise …

The impact of resistance training on brain-derived neurotrophic factor and depression among older adults aged 60 years or older: A systematic review and meta …

S Setayesh, GRM Rahimi - Geriatric Nursing, 2023 - Elsevier
Objective This systematic review and meta-analysis aimed to investigate the impact of
resistance training on brain-derived neurotrophic factor (BDNF) and depression among …

Musculoskeletal deficits and cognitive impairment: epidemiological evidence and biological mechanisms

SX Sui, J Balanta-Melo, JA Pasco, LI Plotkin - Current osteoporosis reports, 2022 - Springer
Abstract Purpose of Review Cognitive impairment is associated with obesity, sarcopenia,
and osteoporosis. However, no critical appraisal of the literature on the relationship between …

Is brain-derived neurotrophic factor a metabolic hormone in peripheral tissues?

ECY Iu, CB Chan - Biology, 2022 - mdpi.com
Simple Summary The activity of brain-derived neurotrophic factor (BDF) in the central
nervous system has been well-studied, but its physiological role in other organs has not …

[HTML][HTML] Myokines may target accelerated cognitive aging in people with spinal cord injury: A systematic and topical review

WAJ Vints, O Levin, N Masiulis, J Verbunt… - Neuroscience & …, 2023 - Elsevier
Persons with spinal cord injury (SCI) can suffer accelerated cognitive aging, even when
correcting for mood and concomitant traumatic brain injury. Studies in healthy older adults …