Leveraging artificial intelligence in the fight against infectious diseases

F Wong, C de la Fuente-Nunez, JJ Collins - Science, 2023 - science.org
Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …

Lateral flow test engineering and lessons learned from COVID-19

J Budd, BS Miller, NE Weckman, D Cherkaoui… - Nature Reviews …, 2023 - nature.com
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …

CRISPR-based diagnostics

MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …

Wearable materials with embedded synthetic biology sensors for biomolecule detection

PQ Nguyen, LR Soenksen, NM Donghia… - Nature …, 2021 - nature.com
Integrating synthetic biology into wearables could expand opportunities for noninvasive
monitoring of physiological status, disease states and exposure to pathogens or toxins …

Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - journals.asm.org
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Biosensors for healthcare: Current and future perspectives

ER Kim, C Joe, RJ Mitchell, MB Gu - Trends in Biotechnology, 2023 - cell.com
Biosensors are utilized in several different fields, including medicine, food, and the
environment; in this review, we examine recent developments in biosensors for healthcare …

Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis

Y Liu, L Zhan, Z Qin, J Sackrison, JC Bischof - ACS nano, 2021 - ACS Publications
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs

M Broto, MM Kaminski, C Adrianus, N Kim… - Nature …, 2022 - nature.com
CRISPR-based diagnostics enable specific sensing of DNA and RNA biomarkers
associated with human diseases. This is achieved through the binding of guide RNAs to a …

CRISPR‐cas biochemistry and CRISPR‐based molecular diagnostics

Z Weng, Z You, J Yang, N Mohammad… - Angewandte Chemie …, 2023 - Wiley Online Library
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …

[HTML][HTML] Face masks in the new COVID-19 normal: materials, testing, and perspectives

MH Chua, W Cheng, SS Goh, J Kong, B Li, JYC Lim… - Research, 2020 - spj.science.org
The increasing prevalence of infectious diseases in recent decades has posed a serious
threat to public health. Routes of transmission differ, but the respiratory droplet or airborne …