A revealing review of mesenchymal stem cells therapy, clinical perspectives and Modification strategies

P Saeedi, R Halabian, AAI Fooladi - Stem cell investigation, 2019 - pmc.ncbi.nlm.nih.gov
Multipotent mesenchymal stem cells (MSCs) have been considerably inspected as effective
tool for cell-based therapy of inflammatory, immune-mediated, and degenerative diseases …

The emerging antioxidant paradigm of mesenchymal stem cell therapy

R Stavely, K Nurgali - Stem Cells Translational Medicine, 2020 - academic.oup.com
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …

[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease

SH Ranganath, O Levy, MS Inamdar, JM Karp - Cell stem cell, 2012 - cell.com
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …

Concise review: adipose‐derived stem cells as a novel tool for future regenerative medicine

H Mizuno, M Tobita, AC Uysal - Stem cells, 2012 - academic.oup.com
The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift that may provide alternative therapeutic solutions …

[HTML][HTML] Adiponectin stimulates exosome release to enhance mesenchymal stem-cell-driven therapy of heart failure in mice

Y Nakamura, S Kita, Y Tanaka, S Fukuda, Y Obata… - Molecular Therapy, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are cultured adult stem cells that originally reside
in virtually all tissues, and the gain of MSCs by transplantation has become the leading form …

Mesenchymal stem cells as therapeutics

B Parekkadan, JM Milwid - Annual review of biomedical …, 2010 - annualreviews.org
Mesenchymal stem cells (MSCs) are multipotent cells that are being clinically explored as a
new therapeutic for treating a variety of immune-mediated diseases. First heralded as a …

Mesenchymal stem cell therapy: Two steps forward, one step back

J Ankrum, JM Karp - Trends in molecular medicine, 2010 - cell.com
Mesenchymal stem cell (MSC) therapy is poised to establish a new clinical paradigm;
however, recent trials have produced mixed results. Although MSC were originally …

Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions

R Quertainmont, D Cantinieaux, O Botman, S Sid… - PloS one, 2012 - journals.plos.org
Numerous strategies have been managed to improve functional recovery after spinal cord
injury (SCI) but an optimal strategy doesn't exist yet. Actually, it is the complexity of the …

Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure

DS Zagoura, MG Roubelakis, V Bitsika, O Trohatou… - Gut, 2012 - gut.bmj.com
Background There is increasing interest in the therapeutic potential of human mesenchymal
stem cells (hMSCs), especially in diseases such as acute hepatic failure (AHF) that are …

Safety and efficacy of injection of human placenta mesenchymal stem cells derived exosomes for treatment of complex perianal fistula in non‐Crohn's cases: Clinical …

H Pak, A Hadizadeh, A Heirani‐Tabasi… - Journal of …, 2023 - Wiley Online Library
Background and Aim A perianal fistula is an abnormal tract that connects anal canal to skin.
Current medical and surgical interventions have a high failure rate particularly in complex …