Systemic sclerosis (SSc) is an autoimmune disease associated with increased mortality and
poor morbidity, impairing the quality of life in patients. Whilst we know that SSc affects …

Inflammatory processes are prominent in various types of human and experimental
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …

Abstract Introduction Systemic sclerosis (SSc) is an autoimmune connective tissue disorder
characterized by fibroproliferative vasculopathy, immunological abnormalities and …

Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …

Scleroderma (systemic sclerosis) is associated with several autoantibodies, each of which is
useful in the diagnosis of affected patients and in determining their prognosis. Anti …

Pulmonary arterial hypertension (PAH), corresponding to group 1 of pulmonary
hypertension classification, is a rare disease with a major prognostic impact on morbidity …

Pulmonary arterial hypertension (PAH) is the leading cause of death in systemic sclerosis
(SSc) and affects up to 12% of all patients with SSc, with a 50% mortality rate within 3 years …

Systemic sclerosis (SSc) is thought to be an autoimmune disease, as autoantibodies against
a variety of extractable nuclear antigens can be detected in patient sera. Subgrou** …

Idiopathic pulmonary fibrosis (IPF) is a disabling disease of the lung parenchyma,
characterized by progressive accumulation of scar tissue and myofibroblast activation after …

The association between autoimmunity and pulmonary arterial hypertension (PAH) has
been appreciated for> 40 yrs, but how autoimmune injury might contribute to the …