Cancer-associated cachexia
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …
Cancer cachexia: a nutritional or a systemic inflammatory syndrome?
Cancer cachexia has long been perceived as a nutritional syndrome. However, nutritional
interventions have continued to be ineffective. With the recent recognition of the importance …
interventions have continued to be ineffective. With the recent recognition of the importance …
The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first …
G Fucà, V Guarini, C Antoniotti, F Morano… - British journal of …, 2020 - nature.com
Abstract Background Immune-inflammatory biomarkers (IIBs) showed a prognostic
relevance in patients with metastatic CRC (mCRC). We aimed at evaluating the prognostic …
relevance in patients with metastatic CRC (mCRC). We aimed at evaluating the prognostic …
[HTML][HTML] Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines
GB Crawford, T Dzierżanowski, K Hauser, P Larkin… - ESMO open, 2021 - Elsevier
In palliative care (PC), the term 'end of life'(EoL) is commonly used but inconsistently
defined. 1 This European Society for Medical Oncology (ESMO) Clinical Practice Guideline …
defined. 1 This European Society for Medical Oncology (ESMO) Clinical Practice Guideline …
Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance
AE Tuomisto, MJ Mäkinen… - World journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …
The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: systematic review and meta-analysis
Cancer remains a leading causes of death worldwide and an elevated systemic
inflammatory response (SIR) is associated with reduced survival in patients with operable …
inflammatory response (SIR) is associated with reduced survival in patients with operable …
The impact of everyday stressors on the immune system and health
A Seiler, CP Fagundes, LM Christian - Stress challenges and immunity in …, 2020 - Springer
Research over the past three to four decades has clearly established that psychological
stress affects clinically relevant immune system outcomes, including inflammatory …
stress affects clinically relevant immune system outcomes, including inflammatory …
Diagnostic sensitivity of NLR and PLR in early diagnosis of gastric cancer
T Fang, Y Wang, X Yin, Z Zhai, Y Zhang… - Journal of …, 2020 - Wiley Online Library
The neutrophil‐lymphocyte ratio (NLR) and the platelet‐lymphocyte ratio (PLR) are markers
of systemic inflammation. However, there is little evidence of the value of inflammation in the …
of systemic inflammation. However, there is little evidence of the value of inflammation in the …
Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review
Background Computed tomography (CT) analysis of body composition has garnered interest
as a potential prognostic tool in those with cancer. A range of pre‐defined thresholds …
as a potential prognostic tool in those with cancer. A range of pre‐defined thresholds …
Prognostication in advanced cancer: update and directions for future research
The objective of this review is to provide an update on prognostication in patients with
advanced cancer and to discuss future directions for research in this field. Accurate …
advanced cancer and to discuss future directions for research in this field. Accurate …