Superoxide ion: generation and chemical implications

M Hayyan, MA Hashim, IM AlNashef - Chemical reviews, 2016 - ACS Publications
Superoxide ion (O2•–) is of great significance as a radical species implicated in diverse
chemical and biological systems. However, the chemistry knowledge of O2•–is rather …

Antioxidant peptides, the guardian of life from oxidative stress

Y Zhu, K Wang, X Jia, C Fu, H Yu… - Medicinal Research …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …

A Redox Modulatory Mn3O4 Nanozyme with Multi‐Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model

N Singh, MA Savanur, S Srivastava… - Angewandte …, 2017 - Wiley Online Library
Nanomaterials with enzyme‐like activities (nanozymes) attracts significant interest due to
their therapeutic potential for the treatment of various diseases. Herein, we report that a …

Limitations of the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays

A Van Tonder, AM Joubert, AD Cromarty - BMC research notes, 2015 - Springer
Background The tetrazolium-based MTT assay has long been regarded as the gold
standard of cytotoxicity assays as it is highly sensitive and has been miniaturised for use as …

A cerium vanadate nanozyme with specific superoxide dismutase activity regulates mitochondrial function and ATP synthesis in neuronal cells

N Singh, SK NaveenKumar… - Angewandte Chemie …, 2021 - Wiley Online Library
Nanoparticles that functionally mimic the activity of metal‐containing enzymes (metallo‐
nanozymes) are of therapeutic importance for treating various diseases. However, it is still …

Oxidative stress and neurodegenerative disorders

J Li, WO, W Li, ZG Jiang, HA Ghanbari - International journal of molecular …, 2013 - mdpi.com
Living cells continually generate reactive oxygen species (ROS) through the respiratory
chain during energetic metabolism. ROS at low or moderate concentration can play …

Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction

MV Berridge, PM Herst, AS Tan - Biotechnology annual review, 2005 - Elsevier
Tetrazolium salts have become some of the most widely used tools in cell biology for
measuring the metabolic activity of cells ranging from mammalian to microbial origin. With …

Antioxidative and antidiabetic effects of natural polyphenols and isoflavones

A Umeno, M Horie, K Murotomi, Y Nakajima, Y Yoshida - Molecules, 2016 - mdpi.com
Many polyphenols that contain more than two phenolic hydroxyl groups are natural
antioxidants and can provide health benefits to humans. These polyphenols include, for …

Detection methodologies and mechanisms of reactive oxygen species generated in Fenton/Fenton-like processes

C Zhang, L Liu, Y Pan, R Qin, W Wang, M Zhou… - Separation and …, 2024 - Elsevier
As one of the most popular advanced oxidation processes (AOPs), Fenton/Fenton-like
processes are of great importance in degrading recalcitrant contaminants with high …

Comparative study on the effect of dietary β-carotene and phycocyanin extracted from Spirulina platensis on immune-oxidative stress biomarkers, genes expression …

MS Hassaan, EY Mohammady, MR Soaudy… - Fish & Shellfish …, 2021 - Elsevier
The current trial investigated the roles of β-carotene and phycocyanin extracted from
Spirulina platensis on growth, serum biochemical, digestive enzymes, antioxidant defense …