The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State‐of‐the‐Art Review

SA Moosavian, T Sathyapalan… - Bioinorganic …, 2021 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …

Anti-aging properties of phytoconstituents and phyto-nanoemulsions and their application in managing aging-related diseases

F Xue, X Li, L Qin, X Liu, C Li, B Adhikari - Advanced Drug Delivery …, 2021 - Elsevier
Aging is spontaneous and inevitable process in all living beings. It is a complex natural
phenomenon that manifests as a gradual decline of physiological functions and …

Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/PPARα-NF-κB/IR-S2 signaling …

D Reda, GE Elshopakey, TA Albukhari… - Frontiers in …, 2023 - frontiersin.org
Introduction: Nonalcoholic fatty liver disease (NAFLD) is a chronic disease characterized by
fat deposits in liver cells, which can lead to hepatitis and fibrosis. This study attempted to …

Long-term and liver-selected ginsenoside C–K nanoparticles retard NAFLD progression by restoring lipid homeostasis

C Yue, D Li, S Fan, F Tao, Y Yu, W Lu, Q Chen, A Yuan… - Biomaterials, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent hepatic disease
characterized as lipid accumulation, yet without any approved drug. And development of …

[HTML][HTML] VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats

H Chen, H Zhang, A Li, Y Liu, Y Liu, W Zhang, C Yang… - Redox biology, 2024 - Elsevier
Purpose To investigate the regulatory effect and mechanism of Vitamin D receptor (VDR) on
mitochondrial function in renal tubular epithelial cell under diabetic status. Methods The …

Fortification of Plant-Based Milk with Calcium May Reduce Vitamin D Bioaccessibility: An In Vitro Digestion Study

H Zhou, B Zheng, Z Zhang, R Zhang, L He… - Journal of Agricultural …, 2021 - ACS Publications
Many plant-based milks lack key micronutrients found in bovine milk, such as calcium and
vitamin D. In this study, we fortified almond milk with these two micronutrients and used a …

AdipoRon, an adiponectin receptor agonist, modulates AMPK signaling pathway and alleviates ovalbumin-induced airway inflammation in a murine model of asthma

MM Samaha, MM El-Desoky, FA Hisham - International …, 2024 - Elsevier
Asthma is a long-term disease that causes airways swelling and inflammation and in turn
airway narrowing. AdipoRon is an orally active synthetic small molecule that acts as a …

Bioavailability by design—Vitamin D3 liposomal delivery vehicles

P Dałek, D Drabik, H Wołczańska, A Foryś… - … , Biology and Medicine, 2022 - Elsevier
Vitamin D3 deficiency has serious health consequences, as demonstrated by its effect on
severity and recovery after COVID-19 infection. Because of high hydrophobicity, its …

Oxidative Stress as a Target for Non-Pharmacological Intervention in MAFLD: Could There Be a Role for EVOO?

A Seidita, A Cusimano, A Giuliano, M Meli, A Carroccio… - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a central role in most chronic liver diseases and, in particular, in
metabolic dysfunction-associated fatty liver disease (MAFLD), the new definition of an old …

Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats

HM **a, J Wang, XJ **e, LJ Xu… - … journal of molecular …, 2019 - spandidos-publications.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin
resistance and inflammation; however, the exact pathogenesis of NAFLD is not fully …