Cellular pathways that repair chromosomal double-strand breaks (DSBs) have pivotal roles
in cell growth, development and cancer. These DSB repair pathways have been the target of …

DNA polymerase θ (Pol θ) is a DNA repair enzyme widely conserved in animals and plants.
Pol θ uses short DNA sequence homologies to initiate repair of double-strand breaks by …

Attenuated strains of the naturally occurring plant pathogen Agrobacterium tumefaciens can
transfer virtually any DNA sequence of interest to model plants and crops. This has made …

Agrobacterium species transfer DNA (T− DNA) to plant cells where it may integrate into plant
chromosomes. The process of integration is thought to involve invasion and ligation of T …

In vitro and ex vitro Agrobacterium rhizogenes-mediated hairy root transformation (HRT)
assays are key components of the plant biotechnology and functional genomics toolkit. In …

Main conclusion Plant responds to Agrobacterium via three-layered immunity that
determines its susceptibility or resistance to Agrobacterium infection. Abstract Agrobacterium …

Maintenance of genomic integrity is critical for the perpetuation of all forms of life including
humans. Living organisms are constantly exposed to stress from internal metabolic …

Agrobacterium tumefaciens, a pathogenic bacterium capable of transforming plants through
horizontal gene transfer, is nowadays the preferred vector for plant genetic engineering. The …

In eukaryotes, double‐strand breaks (DSBs) are either repaired by homologous
recombination (HR) or non‐homologous end‐joining (NHEJ). In somatic plant cells, HR is …

Although clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas)-mediated gene editing has revolutionized biology and plant …