Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Rescuing the last-line polymyxins: achievements and challenges

SC Nang, MAK Azad, T Velkov, QT Zhou, J Li… - Pharmacological …, 2021 - Elsevier
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Bactericidal and cytotoxic properties of silver nanoparticles

C Liao, Y Li, SC Tjong - International journal of molecular sciences, 2019 - mdpi.com
Silver nanoparticles (AgNPs) can be synthesized from a variety of techniques including
physical, chemical and biological routes. They have been widely used as nanomaterials for …

Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Biofilm formation and antibiotic resistance of Klebsiella pneumoniae isolated from clinical samples in a tertiary care hospital, Klaten, Indonesia

H Nirwati, K Sinanjung, F Fahrunissa, F Wijaya… - BMC proceedings, 2019 - Springer
Background Klebsiella pneumoniae (K. pneumoniae) is a common cause of health-care
associated infections (HAIs) and has high levels of antibiotic resistance. These bacteria are …

[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria

Y Liu, Z Tong, J Shi, R Li, M Upton, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

Hypervirulent klebsiella pneumoniae

TA Russo, CM Marr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …

Evaluation of antibiotic resistance mechanisms in gram-negative bacteria

A Gauba, KM Rahman - Antibiotics, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing
one of the most urgent global healthcare and economic threats. Due to the lack of new …

Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms

Q Yang, M Li, OB Spiller, DO Andrey… - Nature …, 2017 - nature.com
MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here,
we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness …

Nonribosomal antibacterial peptides that target multidrug-resistant bacteria

Y Liu, S Ding, J Shen, K Zhu - Natural product reports, 2019 - pubs.rsc.org
Covering: 2000 to 2018, particularly from 2010 to early 2018 The increase in the incidence
of antibiotic resistant infections is threatening to overwhelm healthcare practices worldwide …