Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …

Cardiac allograft vasculopathy (CAV) is a pathologic immune-mediated remodelling of the
vasculature in transplanted hearts and, by impairing perfusion, is the major cause of late …

Background—Atherosclerosis is an inflammatory disease in which interferon (IFN)-γ, the
signature cytokine of Th1 cells, plays a central role. We investigated whether interleukin (IL) …

Background. Composite tissue transplantation effectively reconstructs the most complex
defects, but its use is limited because of harmful immunosuppression and the high …

Giant cell arteritis (GCA) is a granulomatous systemic vasculitis of large-and medium-sized
arteries that affects the elderly. In recent years, advances in diagnostic imaging have …

Inflammatory arterial diseases differentially affect the compartments of the vessel wall. The
intima and adventitia are commonly involved by the disease process, with luminal and …

Cardiac allograft vasculopathy is the major cause of late graft loss in heart transplant
recipients. Histological studies of characteristic end-stage lesions reveal arterial changes …

Graft vascular disease (GVD) is the single most important long-term limitation to solid-organ
transplantation. It is a concentric vascular intimal hyperplastic lesion composed of smooth …

Abstract Purpose of Review Hypertension is a common disorder with substantial impact on
public health due to highly elevated cardiovascular risk. The mechanisms still remain …

Our understanding of the molecular pathways that control immune responses, particularly
immunomodulatory molecules that control the extent and duration of an immune response …