Cognitive function following a major depressive episode: a systematic review and meta-analysis

M Semkovska, L Quinlivan, T O'Grady… - The Lancet …, 2019 - thelancet.com
Background Substantial evidence suggests that cognitive deficits might persist after
remission of a major depressive episode. However, results are inconsistent relative to the …

Relationship between depression and frailty in older adults: a systematic review and meta-analysis

P Soysal, N Veronese, T Thompson, KG Kahl… - Ageing research …, 2017 - Elsevier
Aim Depression and frailty are prevalent and burdensome in older age. However, the
relationships between these entities are unclear and no quantitative meta-analysis exists …

Safety, tolerability, and risks associated with first-and second-generation antipsychotics: a state-of-the-art clinical review

M Solmi, A Murru, I Pacchiarotti… - … and clinical risk …, 2017 - Taylor & Francis
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …

The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: a critical review of the literature

AF Carvalho, MS Sharma, AR Brunoni… - Psychotherapy and …, 2016 - karger.com
Newer generation antidepressant drugs (ADs) are widely used as the first line of treatment
for major depressive disorders and are considered to be safer than tricyclic agents. In this …

Cognitive functioning in the first-episode of major depressive disorder: A systematic review and meta-analysis.

E Ahern, M Semkovska - Neuropsychology, 2017 - psycnet.apa.org
Objective: Cognitive deficits are frequently observed in major depression. Yet, when these
deficits emerge and how they relate to the depressed state is unclear. The aim of this 2-part …

Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders

T Prévot, E Sibille - Molecular psychiatry, 2021 - nature.com
Cognitive dysfunctions, including impaired attention, learning, memory, planning and
problem solving, occur in depressive episodes, often persist during remission, predict …

Aerobic exercise as a tool to improve hippocampal plasticity and function in humans: practical implications for mental health treatment

A Kandola, J Hendrikse, PJ Lucassen… - Frontiers in human …, 2016 - frontiersin.org
Aerobic exercise (AE) has been widely praised for its potential benefits to cognition and
overall brain and mental health. In particular, AE has a potent impact on promoting the …

A hypothesis of monoamine (5-HT)–glutamate/GABA long neural circuit: aiming for fast-onset antidepressant discovery

YF Li - Pharmacology & therapeutics, 2020 - Elsevier
Major depressive disorder has become a global public health problem of serious concern.
Most of the clinical antidepressants are developed under the classic “monoamine …

Apelin-13 suppresses neuroinflammation against cognitive deficit in a streptozotocin-induced rat model of Alzheimer's disease through activation of BDNF-TrkB …

H Luo, Y **ang, X Qu, H Liu, C Liu, G Li… - Frontiers in …, 2019 - frontiersin.org
Alzheimer's disease (AD), a progressive neurodegenerative disease characterized by
impairments of cognitive function as a result of synaptic deficits and neuronal loss, is …

Shared metabolic and immune-inflammatory, oxidative and nitrosative stress pathways in the metabolic syndrome and mood disorders

LGP de Melo, SOV Nunes, G Anderson… - Progress in Neuro …, 2017 - Elsevier
This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …